Russian Medical Inquiry
(RMZh. Meditsinskoe Obozrenie) ISSN 2587-6821 (Print), 2686-9918 (Online)

Common helminthiases in pediatric practice

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DOI: 10.32364/2618-8430-2024-7-3-13

S.V. Belmer

Pirogov Russian National Research Medical University, Moscow, Russian Federation

Enterobiasis and ascariasis are the most prevalent helminthic diseases encountered in pediatric practice within the Russian Federation. Both diseases are caused by roundworms, namely pinworms and ascarids, respectively. Pinworm parasites in the intestines of a child. Female pin-worms emerge from the anus and deposit eggs in the perianal folds, which is accompanied by severe pruritus, the primary symptom of this disease. Reinfection may result from scratching the perianal region and subsequent ingestion of eggs. The treatment of enterobiasis commences with the implementation of a patient hygiene regimen to prevent reinfection. Pharmacological treatment entails the administration of albendazole, mebendazole, and pyrantel. Ascaridosis is a geohelminth disease. In the absence of adherence to established hygiene protocols, ascarid eggs may gain access to the body from the external environment. Ascarid larvae from the intestines may gain access to the lungs via the bloodstream, resulting in the development of respiratory symptoms. Adult worms reside in the intestines and cause abdominal discomfort. Albendazole is an efficacious and safe medication for the treatment of ascaridosis in children. It is of the utmost importance to diagnose helminth infections at an early stage and to implement preventative measures. The most effective method of prevention is adherence to personal hygiene practices. These factors are of the utmost importance in further reducing the incidence of helminth infections.

Keywords: enterobiasis, pinworms, ascaridosis, ascarids, symptoms, diagnostics, treatment, prevention, albendazole.

For citation: Belmer S.V. Common helminthiases in pediatric practice. Russian Journal of Woman and Child Health. 2024;7(3):281–285 (in Russ.). DOI: 10.32364/2618-8430-2024-7-3-13.

About the author:

Sergey V. Belmer — Dr. Sc. (Med.), professor of the Department Hospital Pediatrics No. 2 of the Pediatric Faculty, Pirogov Russian National Research Medical University; 1, Ostrovityanov str., Moscow, 117437, Russian Federation; ORCID iD 0000-0002-1228-443X.

Contact information: Sergey V. Belmer, e-mail: belmersv@mail.ru.

Financial Disclosure: the author has no a financial or property interest in any material or method mentioned.

There is no conflict of interest.

Received 18.07.2024.

Revised 12.08.2024.

Accepted 04.09.2024.

References
1. Гончар Н.В. Паразитарные заболевания. Энтеробиоз. В кн.: Болезни кишечника у детей. Под ред. Бельмера С.В., Разумовского А.Ю., Хавкина А.И. Т. 2. М.: ИД «МЕДПРАКТИКА-М». 2018:366–371.Gonchar N.V. Parasitic diseases. Enterobiasis. In: Intestinal diseases in children. Belmer S.V., Razumovsky A.Yu., Khavkin A.I., eds. V. 2. M.: ID "MEDPRAKTIKA-M", 2018:366–371 (in Russ.).
2. Wendt S., Trawinski H., Schubert S. et al. The Diagnosis and Treatment of Pinworm Infection. Dtsch Arztebl Int. 2019;116(13):213–219. DOI: 10.3238/arztebl.2019.0213.
3. Leung A.K.C., Lam J.M., Barankin B. et al. Pinworm (Enterobius Vermicularis) Infestation: An Updated Review. Curr Pediatr Rev. 2024. DOI: 10.2174/0115733963283507240115112552. Online ahead of print.
4. Hulínská D. Morphogenesis and viability of larvae in the eggs of Enterobius vermicularis. Folia Parasitol (Praha). 1974;21(3):225–232.
5. Von Höveling A., Carrasco L., Weitzel T. et al. Preschool Girl With Vaginal Bleeding Due to Pinworm Endometritis. J Pediatr Adolesc Gynecol. 2020;33(2):170–172. DOI: 10.1016/j.jpag.2019.12.004.
6. St. Georgiev V. Chemotherapy of enterobiasis (oxyuriasis). Expert Opin Pharmacother. 2001;2(2):267–275. DOI: 10.1517/14656566.2.2.267.
7. Pyzocha N., Cuda A. Common Intestinal Parasites. Am Fam Physician. 2023;108(5):487–493.
8. Chai J.Y., Jung B.K., Hong S.J. Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update. Korean J Parasitol. 2021;59(3):189–225. DOI: 10.3347/kjp.2021.59.3.189.
9. Ibarra J. Threadworms: a starting point for family hygiene. Br J Community Nurs. 2001;6(8):414–420. DOI: 10.12968/bjcn.2001.6.8.7058.
10. Mehlhorn H. Die Parasiten des Menschen: Erkrankungen erkennen, bekämpfen und vorbeugen. XIInd ed. Springer Spektrum Verlag; 2022.
11. Richter J., Häussinger D., Mehlhorn H. Madenwurminfektion: Eine häufige, aber wenig beachtete Parasitose. Dtsch Arztebl. 2003;100:A 2771.
12. Shimizu H., Ito S. Successful Resolution of Recurrent Vaginal Pinworm Infection With Intermittent Albendazole Administration. Pediatr Infect Dis J. 2020;39(3):254–255. DOI: 10.1097/INF.0000000000002546.
13. Гончар Н.В. Паразитарные заболевания. Аскаридоз. В кн.: Болезни кишечника у детей. Под ред. Бельмера С.В., Разумовского А.Ю., Хавкина А.И. Т. 2. М.: ИД «МЕДПРАКТИКА-М», 2018:297–304.Gonchar N.V. Parasitic diseases. Ascariasis. In: Intestinal diseases in children. Belmer S.V., Razumovsky A.Yu., Khavkin A.I., eds. V. 2. M.: ID "MEDPRAKTIKA-M", 2018:297–304 (in Russ.).
14. Montresor A., Mupfasoni D., Mikhailov A. et al. The global progress of soil-transmitted helminthiases control in 2020 and World Health Organization targets for 2030. PLoS Negl Trop Dis. 2020;14(8):e0008505. DOI: 10.1371/journal.pntd.0008505.
15. Holland C., Sepidarkish M., Deslyper G. et al. Global prevalence of Ascaris infection in humans (2010-2021): a systematic review and meta-analysis. Infect Dis Poverty. 2022;11(1):113. DOI: 10.1186/s40249-022-01038-z.
16. Bekele T., Lachisa L., Tsegaye A. et al. Efficacy of Albendazole and Mebendazole Against Soil Transmitted Infections among Pre-School and School Age Children: A Systematic Review and Meta-Analysis. J Epidemiol Glob Health. 2024. DOI: 10.1007/s44197-024-00231-7. Online ahead of print.
17. Assefa A., Damtie D., Abeje G. et al. Efficacy of 400 mg albendazole against soil-transmitted helminthes among Salgy Primary School Children, Dembia district, Northwest Ethiopia, 2020. "Uncontrolled experimental study". Health Sci Rep. 2024;7(4):e2041. DOI: 10.1002/hsr2.2041.
18. Hon K.L., Leung A.K.C. An update on the current and emerging pharmacotherapy for the treatment of human ascariasis. Expert Opin Pharmacother. 2024. DOI: 10.1080/14656566.2024.2319686. Online ahead of print.
19. Solaymani-Mohammadi S., Genkinger J.M., Loffredo C.A., Singer S.M. A meta-analysis of the effectiveness of albendazole compared with metronidazole as treatments for infections with Giardia duodenalis. PLoS Negl Trop Dis. 2010;4(5):e682. DOI: 10.1371/journal.pntd.0000682.
20. Horton J. Albendazole: a review of anthelmintic efficacy and safety in humans. Parasitology. 2000;121 Suppl:S113–S132. DOI: 10.1017/s0031182000007290.
21. Savioli L., Albonico M., Daumerie D. et al. Review of the 2017 WHO Guideline: Preventive chemotherapy to control soil-transmitted helminth infections in at-risk population groups. An opportunity lost in translation. PLoS Negl Trop Dis. 2018;12(4):e0006296. DOI: 10.1371/journal.pntd.0006296.

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