Immunomodulatory effects of probiotics: possibilities of acute respiratory infections prevention in children
DOI: 10.32364/2618-8430-2024-7-3-12
S.V. Nikolaeva, O.O. Pogorelova, E.K. Shushakova, A.V. Gorelov
Central Research Institute of Epidemiology of the Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, Moscow, Russian Federation
Acute respiratory infections (ARIs) currently represent a major health concern in pediatric populations, accounting for up to 90% of all acute respiratory tract infection cases. While the efficacy of probiotics in treating various diseases is well-established, their potential role as a preventive measure to enhance the body's resistance against ARIs is garnering increased attention. Numerous clinical studies involving children have demonstrated that probiotics can reduce the incidence of ARIs, decrease the average duration of ARI episodes, lower the frequency of antibiotic usage, and decrease the number of school or preschool days missed due to illness. The careful selection of probiotic strains — considering their safety, tolerability, and varied physiological effects — has led to the development of several clinically effective probiotics in the market. This article reviews key data supporting the efficacy of Lactobacillus plantarum 7315/7316 in clinical practice.
Keywords: probiotic, prevention, Lactobacillus plantarum, children, microbiota, immunity.
For citation: Nikolaeva S.V., Pogorelova O.O., Shushakova E.K., Gorelov A.V. Immunomodulatory effects of probiotics: possibilities of acute respiratory infections prevention in children. Russian Journal of Woman and Child Health. 2024;7(3):276–280 (in Russ.). DOI: 10.32364/2618-8430-2024-7-3-12.
About the authors:
Svetlana V. Nikolaeva — Dr. Sc. (Med.), leading researcher of the Clinical Division of Infectious Disorders, Central
Research Institute of Epidemiology of the Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; 3A, Novogireevskaya str., Moscow, 111123, Russian Federation; ORCID iD 0000-0003-3880-8112.
Olga O. Pogorelova — C. Sc. (Med.), Researcher at the Clinical Department of Infectious Pathology, Central Research Institute of Epidemiology of the Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; 3A, Novogireevskaya str., Moscow, 111123, Russian Federation.
Ekaterina K. Shushakova — C. Sc. (Med.), Junior Researcher at the Clinical Department of Infectious Pathology, Central Research Institute of Epidemiology of the Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being; 3A, Novogireevskaya str., Moscow, 111123, Russian Federation; ORCID iD 0000-0003-2619-9110.
Aleksandr V. Gorelov — Dr. Sc. (Med.), Professor, Academician of RAS, Deputy Director for Scientific Work, Central Research Institute of Epidemiology of the Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, 3A, Novogireevskaya str., Moscow, 111123, Russian Federation; ORCID iD 0000-0001-9257-0171.
Contact information: Svetlana V. Nikolaeva, e-mail: nikolaeva008@list.ru.
Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.
There is no conflict of interest.
Received 04.07.2024.
Revised 24.07.2024.
Accepted 15.08.2024
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