Prevention of dry eye syndrome in chronic demodex blepharitis
T.N. Safonova¹, N.P. Kintyukhina¹, A.E. Petrenko², O.V. Gladkova<sup>1

1</sup> Research Institute of Eye Diseases, Moscow, Russia
² Ltd «Stark», Moscow, Russia

Aim: to assess the possibility of prevention of dry eye syndrome in the treatment of chronic blepharitis demodectic etiology cream-gel Deksodem Phyto on the basis of clinical, functional presentations and study akarogramm. 
Material and methods. We observed 74 patients (148 eyes) with chronic blepharitis demodicosis etiology. The main group included 39 patients (78 eyes) 2 times a day 45 days used cream-gel Deksodem Phyto. The average age of the patients was 67,06±7,94 years. The control group included 35 patients (70 eyes) who underwent standard therapy. The average age – 63,2±8,1 years. Patients underwent conventional ophthalmic examination, questionnaires (SPEED, Standard Patient Evaluation of Eye Dryness), the Schirmer I test and tear break-up time. In addition we determined the number of functional meibomian glands, compression test was assessed by scoring system: score 0 corresponded to positive samples, 1 point – negative sample (stenosis of the meibomian glands), grade 2 – negative sample (obstruction). Laboratory diagnosis included the determination of Demodex spp. on the eyelids and on the skin. Additionally, carried out the microbiological study of the state of the conjunctiva. The follow-up period was 6 months. 
Results. Long-term therapy with Deksodem Phyto has yielded positive clinical and laboratory results in the form of stabilization of the tear film, restore the function of the meibomian glands, the destruction of Demodex spp. minimize recurrence of the infestation. Conclusion. Therapy of chronic Demodex blepharitis Deksodem Phyto aimed at preventing dry eye syndrome and has a double effect - acaricide and moisturizing.
Keywords: blepharitis, demodex, dry eye syndrome.
For citation: Safonova T.N. , Kintyukhina N.P. , Petrenko A.E. et al. Prevention of dry eye syndrome in chronic demodex blepharitis // RMJ. Clinical ophthalmology. 2016. № 2. P. 89–93.