Epidemiological analysis primary open-angle glaucoma incidence and prevalence in Russia
DOI: 10.32364/2311-7729-2022-22-1-3-10
A.B. Movsisyan1,2, A.V. Kuroedov1,3, M.A. Arkharov4, V.V. Prokhorenko4, I.A.Chepurnov4
1Pirogov Russian National Research Medical University, Moscow, Russian Federation
2Hospital for War Veterans No. 2, Moscow, Russian Federation
3P.V. Mandryka Military Clinical Hospital, Moscow, Russian Federation
4N.E. Bauman Moscow State Technical University, Moscow, Russian Federation
Background: more than 50% of newly diagnosed primary open-angle glaucoma (POAG) patients are in the moderate or advanced stages. It is difficult to assess disease course due to limited official data. On a national scale, prevalence and incidence are measures that hardly provide a complete "landscape" of this issue in Russia.
Aim: to determine the prognosis of changes in epidemiological indicators (prevalence and incidence) of POAG in Russia, assess disease duration and calculate presumed age of disease onset.
Patients and Methods: we applied a scientific-analytical design implying literary statistical analysis of official epidemiological indicators of glaucoma in Russia and multicenter trials. These data were a basis for prediction (three variants) of glaucoma incidence and prevalence in Russia and the development of a mathematical model to determine the age of disease onset and duration.
Results: the age of patients with POAG stage 0 was 54 (49;58) yea rs. This age was calculated based on data from publications in 2000–2016. These data were initially used to calculate the mean duration of each glaucoma stage. As a result, the "true" age of stage 1 onset was 57 (52;61) years. Meanwhile, the mean age of stage 1 diagnosis was 60 (56;65) years. According to these calculations and considering predicted changes in population size and average life expectancy, a growth in glaucoma incidence and prevalence is expected in low, medium, and high population projections.
Conclusions: we demonstrated an expected growth in glaucoma incidence and prevalence in Russia in the coming 15 years. An increase in visual disability and, therefore, rapid loss of working capacity in various age groups due to "late" diagnosis and treatment are also likely. Collection of epidemiological data, further analysis of these findings, and searching for ways to improve diagnosis and course of socially significant diseases (e.g., glaucoma) are among strate gic tasks for the healthcare system.
Keywords: primary open-angle glaucoma, glaucoma diagnosis, glaucoma epidemiology, prognosis.
For citation: Movsisyan A.B., Kuroedov A.V., Arkharov M.A. et al. Epidemiological analysis primary open-angle glaucoma incidence and prevalence in Russia. Russian Journal of Clinical Ophthalmology. 2022;22(1):3–10 (in Russ.). DOI: 10.32364/2311-7729-2022-22-1-3-10.
About the authors:
1,2Anna B. Movsisyan — ophthalmologist, assistant of the A.P. Nesterov Department of Ophthalmology of the Medical Faculty; ORCID iD 0000-0001-8233-0385.
1,3Aleksandr V. Kuroyedov — Dr. Sc. (Med.), Professor of the Department of Ophthalmology; Head of the Division of Ophthalmology; ORCID iD 0000-0001-9606-0566.
4Mikhail A. Arkharov — student of the 5th course; ORCID iD 0000-0002-4562-8569.
4Vladimir V. Prokhorenko — student of the 2nd course; ORCID iD 0000-0001-5575-0181.
4Ilya A. Chepurnov — C. Sc. (Tech.), Professor of the Military Training Center; ORCID iD 0000-0003-2982-994Х.
1Pirogov Russian National Research Medical University, 1, Ostrovityanov str., Moscow, 117437, Russian Federation.
2Hospital for War Veterans No. 2, 168, Volgogradskiy av., Moscow, 109472, Russian Federation.
3P.V. Mandryka Military Clinical Hospital, 8A, Bolshaya Olenya str., Moscow, 107014, Russian Federation.
4N.E. Bauman Moscow State Technical University, 5 Build. 1, 2nd Baumanskaya str., Moscow, 105005, Russian Federation.
Contact information: Anna B. Movsisyan, e-mail: anna.movs@inbox.ru.
Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.
There is no conflict of interests.
Received 06.09.2021.
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