Prospects for the use of low-level laser radiation in immunology

O.V. Mislavsky¹, Yu.V. Alekseev², T.G. Fedoskova¹, V.V. Smirnov¹, A.V. Ivanov³, S.R. Mashtakova^1,4

¹National Research Center Institute of Immunology of the Russian Federal Medical Biological Agency, Moscow

²Skobelkin State Scientific Center of Laser Medicine of the Federal Medical and Biological Agency, Moscow

³N.N. Blokhin National Medical Research Center of Oncology, Moscow

⁴Laboratory of the Center of Immunology and Reproduction, Moscow

The article presents modern concepts concerning biological action mechanisms of low-level laser radiation, as well as experimental animal models and modern cell culture studies showing the efficacy of using devices (with power from 30 mW to 250–400 mW) for low-level laser therapy. The article also gives examples of effective clinical use of this therapy type, which affects the immune system of animals and humans.

To reduce allergic inflammation (based on the considered modelled cases on animals), it can be considered to study sources with a wavelength of 660 nm, whereas to reduce inflammatory activity — with a wavelength of 810, 830 and 904 nm. Sources with a wavelength of 1264 to 1270 nm are promising for further study of their therapeutic effects on an allergic patient.

Keywords: low-level laser therapy, laser biomodulation, primary radiation acceptors, light-oxygen effect.

For citation: Mislavsky O.V., Alekseev Yu.V., Fedoskova T.G. et al. Prospects for the use of low-level laser radiation in immunology. RMJ. 2021;10:63–68.