Additive technologies in spinal personalized surgery (experimental study)
DOI: 10.32364/2587-6821-2020-4-2-83-88
I.A. Dotsenko1, V.V. Kotomtsev2, I.D. Medvinskiy1,3, A.V. Savel’ev1, M.A. Botov4
1Ural Research Institute of Phthisiopulmonology — Branch of the National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Ekaterinburg, Russian Federation
2Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russian Federation
3Ural State Medical University, Ekaterinburg, Russian Federation
4The First Russian President B.N. Yeltsin Ural Federal University, Ekaterinburg, Russian Federation
Aim: to compare two techniques of the fixation of spinal motion segments in experimental animals with thoracic vertebral fracture/luxation.
Patients and Methods: 10 animals (dogs) were included in the study group. These animals underwent spinal motion segment fixation by experimental technique using personalized titan plates with the individual shape of the surface adjacent to bone and integrated navigation system (apertures with pre-calculated tilt angle for minimally invasive screw fixation). Titan plates were manufactured preoperatively by a 3D printer technique using additive technologies depending on the anatomy of spinal motion segment of the experimental animal based on the primary computed tomography DICOM imaging. 10 dogs with similar injury which underwent traditional surgery (spinal motion segment fixation using transpedicular screws) were included in the study group.
Results: the groups were matched by the mechanism and level (lower thoracic spine) of the i njury with similar consequences (thoracic vertebral fracture/luxation), age (on average, 3.5 years, 95% CI 2.8–4.2) and weight (on average, 32.4 kg, 95% CI 29.3–35.5) of experimental animals. Postoperatively, the improvement of neurological deficiency and the lack of significant inflammation were reported in the study group. This technique prevents spinal canal perforation when placing screws, reduces intraoperative surgeon and patient radiation exposure, improves the stability of spinal segment fixation, and avoids screw fractures.
Conclusion: this novel technique is a promising surgical modality to manage human spinal motion segment damage of various origin.
Keywords: additive technologies, computed tomography, spinal injuries, preclinical studies, minimally invasive surgery.
For citation: Dotsenko I.A., Kotomtsev V.V., Medvinskiy I.D. et al. Additive technologies in spinal personalized surgery (experimental study). Russian Medical Review. 2020;4(2):83–88. DOI: 10.32364/2587-6821-2020-4-2-83-88.
About the authors:
1Ivan A. Dotsenko — MD, researcher, neurosurgeon, ORCID iD 0000-0002-1897-5274;
2Vyacheslav V. Kotomtsev — MD, PhD, Professor, leading researcher of the Laboratory of Immunophysiology and Immunopharmacology ORCID iD 0000-0001-5232-9244;
1,3 Igor Medvinskiy — MD, PhD, Professor, Head of the Division, professor of the Department of Phthisiopulmonology, ORCID iD 0000-0002-3064-4865;
1Aleksandr V. Savel’ev — MD, PhD, senior researcher, Head of the Department of Diagnostic Radiology, ORCID iD 0000-0001-8100-625X;
4Mikhail A. Botov — senior lecturer of the Department of Mathematics ORCID iD 0000-0002-1157-6895.
1Ural Research Institute of Phthisiopulmonology — Branch of the National Medical Research Center of Phthisiopulmonology and Infectious Diseases. 50, 22nd Parts’ezd str., Ekaterinburg, 620039, Russian Federation.
2Institute of Immunology and Physiology of the Ural Branch of the Russian Academy of Sciences. 106, Pervomaiskaya str., Ekaterinburg, 620049, Russian Federation.
3Ural State Medical University. 3, Repin str., Ekaterinburg, 620028, Russian Federation.
4The First Russian President B.N. Yeltsin Ural Federal
University. 19, Mira str., Ekaterinburg, 620002, Russian Federation.
Contact information: Igor Medvinskiy, e-mail: 2134012@gmail.com. Financial Disclosure: no authors have a financial or property interest in any material or method mentioned. There is no conflict of interests. Received 26.02.2020.
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