Role of antiaggregants and statins in cardiovascular risk reduction: opportunities for fixed combinations
Karpov Yu.A.

National Medical Research Center for Cardiology, Moscow

Cardiovascular risk reduction with decreasing morbidity and mortality from cardiovascular diseases is considered as one of the main tasks of modern cardiological practice and should contribute to an increase in life expectancy in our country. Efficacy and safety of statins and acetylsalicylic acid (ASA) have been confirmed in a large number of randomized trials. The use of statins and ASA in patients with a very high cardiovascular risk to reduce incidence of myocardial infarction, stroke, and vascular death is beyond doubt. In this category of patients, the usage of fixed combinations of statins and ASA opens up new opportunities for improving efficacy through better compliance to treatment. However, the use of the same technologies for primary prevention in people with a relatively low risk of cardiovascular events raises certain doubts. The prescription of ASA and statins to patients without clinical manifestations of atherosclerosis in accordance with modern clinical recommendations should be strictly individual.

Key words: statins, acetylsalicylic acid, prevention of cardiovascular complications, compliance, fixed combinations.
For citation: Karpov Yu.A. Role of antiaggregants and statins in cardiovascular risk reduction: opportunities for fixed combinations // RMJ. 2018. № 6(I). P. 42–45.