Russian Medical Inquiry
(RMZh. Meditsinskoe Obozrenie) ISSN 2587-6821 (Print), 2686-9918 (Online)

COVID-19 vaccination of pregnant women: state-of-the-art

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DOI: 10.32364/2587-6821-2021-5-11-768-772

A.A. Girina1, A.L. Zaplatnikov2, V.I. Svintsitskaya2, S.D. Izhogina2

1Khanty-Mansi State Medical Academy, Khanty-Mansiysk, Russian Federation

2Russian Medical Academy of Continuous Professional Education, Moscow,
Russian Federation

Despite efforts made by the world community to battle the novel coronavirus infection, we are still unable to take complete control of virus spread. One of the causes of this issue is inadequate coverage of vaccination. Meanwhile, disease course in specific populations is associated with the risks of severe complications and lethal outcome. Infection of pregnant women is of particular concern. This paper addresses recent data on vaccination against the COVID-19 infection in pregnant women, including those with risk of severe disease course and unfavorable outcome. Monitoring the health of women infected with SARS-CoV-2 during gestation demonstrates unfavorable effects of the COVID-19 infection on the course and outcome of pregnancy. On the other hand, observational programs have demonstrated that vaccination has no effects on pregnancy course and perinatal outcomes. A view of the WHO and professional associations on the vaccination of pregnant women, particularly those from ri sk groups of severe COVID-19 course, is discussed. The importance of a personalized and balanced approach to COVID-19 vaccination of pregnant women involving the assessment of risks and benefits for the mother and child is emphasized.

Keywords: novel coronavirus infection, COVID-19, vaccination, immunization, pregnant women, risk group.

For citation: Girina A.A., Zaplatnikov A.L., Svintsitskaya V.I., Izhogina S.D. COVID-19 vaccination of pregnant women: state-of-the-art. Russian Medical Inquiry. 2021;5(11):768–772 (in Russ.). DOI: 10.32364/2587-6821-2021-5-11-768-772.

About the authors:

Asiya A. Girina — C. Sc. (Med.), associate professor of the Department of Pharmacology, Clinical Pharmacology, and Pediatrics with the Courses of Immunology and Allergy, Khanty-Mansi State Medical Academy, 40, Mira str., Khanty-Mansiysk, 628011, Russian Federation; ORCID iD 0000-0002-5281-1564.

Andrey L. Zaplatnikov — Dr. Sc. (Med.), Professor, Head of Prof. N.N. Gavryushov Department of Neonatology, professor of Acad. G.N. Speranskiy Department of Pediatrics, Vice-chancellor for Instructional Work, Russian Medical Academy of Continuous Professional Education; 2/1 Barrikadnaya str., Moscow, 125993, Russian Federation; ORCID iD 0000-0003-1303-8318.

Viktoriya I. Svintsitskaya — C. Sc. (Med.), associate professor of the Academician G.N. Speranskiy Department of Pediatrics, Russian Medical Academy of Continuous Professional Education, 2/1, Barrikadnaya str., Moscow, 125993, Russian Federation; ORCID iD 0000-0002-9272-2339.

Sofia D. Izhogina — clinical resident of Prof. N.N. Gavryushov Department of Neonatology, Russian Medical Academy of Continuous Professional Education, 2/1, Barrikadnaya str., Moscow, 125993, Russian Federation; ORCID iD 0000-0002-3480-3659.

Contact information: Andrey L. Zaplatnikov, e-mail: zaplatnikov@mail.ru.

Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.

There is no conflict of interests.

Received 16.11.2021.

Revised 22.11.2021.

Accepted 25.11.2021.

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