Dysphonia: state-of-the-art and treatment tools
DOI: 10.32364/2587-6821-2021-5-11-749-754
S.V. Nikolaeva1, A.B. Turovskiy2, Yu.N. Khlypovka1,3
1Central Research Institute of Epidemiology of the Russian Federal Service for Supervi-sion
of Consumer Rights Protection and Human Well-Being, Moscow, Russian Federation
2V.V. Veresaev City Clinical Hospital No. 81, Moscow, Russian Federation
3Central Clinical Hospital and Polyclinic of the Department for Presidential Affairs,
Moscow, Russian Federation
Dysphonia is a voice disorder manifesting with hoarseness, nasality, weak voice, and vocal fatigue. Being a common complaint, dysphonia is a common cause of medical referral and disability due to absence from work. Voice disorders affect individuals of any age. Meanwhile, voice disorders are more commonly reported in patients over 65 years (29.1%) and children. Moreover, 23.4% of children may have dysphonia at a certain point — this disorder is more common in boys than in girls. There are numerous causes of dysphonia, e.g., head snd neck tumors, neurological, gastrointestinal, or lung diseases, psychological disorders, injuries, iatrogenic injuries, infections, etc. Meanwhile, acute laryngitis, a symptom of acute respiratory infections, is one of the leading causes of dysphonia. The most common causative agents of acute laryngitis are parainfluenza and influenza viruses, adenoviruses, on occasion, respiratory syncytial virus, and viral-bacterial associations. Dysphonia trea tment should be complex and include systemic and topical corticosteroids, antihistamines, mucoactive medications, systemic and topical antibiotics, and combined medications (e.g., Homeovox). Clinical trials have demonstrated their efficacy in adults and children.
Keywords: acute laryngitis, dysphonia, hoarseness, treatment.
For citation: Nikolaeva S.V., Turovskiy A.B., Khlypovka Yu.N. Dysphonia: state-of-the-art and treatment tools. Russian Medical Inquiry. 2021;5(11):749–754 (in Russ.). DOI: 10.32364/2587-6821-2021-5-11-749-754.
About the authors:
Svetlana V. Nikolaeva — C. Sc. (Med.), senior researcher, Central Research Institute of Epidemiology of the Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, 3A, Novogireevskaya str.,
Moscow, 111123, Russian Federation; ORCID iD 0000-0003-3880-8112.
Andrey B. Turovskiy — Dr. Sc. (Med.), Professor, Deputy Head Doctor for Medical Work, V.V. Veresaev City Clinical Hospital No. 81, 10, Lobnenskaya str., Moscow, 127644, Russian Federation.
Yuliya N. Khlypovka — C. Sc. (Med.), junior researcher, Central Research Institute of Epidemiology of the Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being, 3A, Novogireevskaya str., Moscow, 111123, Russian Federation; physician of Children’s Infectious Diseases, Central Clinical Hospital and Polyclinic of the Department for Presidential Affairs, 15, Marshal Timoshenko str., Moscow, 121359, Russian Federation; ORCID iD 0000-0003-4821-676X.
Contact information: Svetlana V. Nikolaeva, e-mail: nikolaeva008@list.ru.
Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.
There is no conflict of interests.
Received 14.09.2021.
Revised 07.10.2021.
Accepted 01.11.2021.
2. Rosa M., Behlau M. Mapping of vocal risk in amateur choir. J Voice. 2017;31(118):e1–e11.
3. Guss J., Sadoughi B., Benson B. Dysphonia in performers: toward a clinical definition of laryngology of the performing voice. J Voice. 2014;28:349–355.
4. Verdolini K., Ramig L.O. Review: occupational risks for voice problems. Logoped Phoniatr Vocol. 2001;26:37–46.
5. Roy N., Merrill R.M., Thibeault S. Prevalence of voice disorders in teachers and the general population. J Speech Lang Hear Res. 2004;47:281–293.
6. Smith E., Lemke J., Taylor M. Frequency of voice problems among teachers and other occupations. J Voice. 1998;12:480–488.
7. Fellman D., Simberg S. Prevalence and risk factors for voice problems among soccer coaches. J Voice. 2017;31(121):9–15.
8. Cohen S.M., Kim J., Roy N. Prevalence and causes of dysphonia in a large treatment — seeking population. Laryngoscope. 2012;122:343–348.
9. Roy N., Merrill R.M., Gray S.D. Voice disorders in the general population: preva-lence, risk factors, and occupational impact. Laryngoscope. 2005;115:1988–1995.
10. Coyle S.M., Weinrich B.D., Stemple J.C. Shifts in relative prevalence of laryngeal pathology in a treatment-seeking population. J Voice. 2001;15:424–440.
11. Titze I.R., Lemke J., Montequin D. Populations in the US workforce who rely on voice as a primary tool of trade: a preliminary report. J Voice. 1997;11:254–259.
12. Roy N., Kim J., Courey M. Voice disorders in the elderly: a national database study. Laryngoscope. 2016;126:421–428.
13. Jones K., Sigmon J., Hock L. Prevalence and risk factors for voice problems among telemarketers. Arch Otolaryngol Head Neck Surg. 2002;128:571–577.
14. Davids T., Klein A.M., Johns M.M. Current dysphonia trends in patients over the age of 65: is vocal atrophy becoming more prevalent? Laryngoscope. 2012;122:332–335.
15. Bhattacharya N. The prevalence of pediatric voice and swallowing problems in the United States. Laryngoscope. 2015;125:746–750.
16. Duff M.C., Proctor A., Yairi E. Prevalence of voice disorders in African American and European American preschoolers. J Voice. 2004;18:348–353.
17. Carding P.N., Roulstone S., Northstone K. The prevalence of childhood dysphonia: a cross-sectional study. J Voice. 2006;20:623–630.
18. Silverman E.M. Incidence of chronic hoarseness among school-age children. J Speech Hear Disord. 1975;40:211–215.
19. Angelillo N., Di Costanzo B., Angelillo M. Epidemiological study on vocal disorders in paediatric age. J Prev Med Hyg. 2008;49:1–5.
20. Benninger M.S., Holy C.E., Bryson P.C., Milstein C.F. Prevalence and Occupation of Patients Presenting With Dysphonia in the United States. J Voice. 2017;31(5):594–600. DOI: 10.1016/j.jvoice.2017.01.011.
21. Cohen S.M., Dupont W.D., Courey M.S. Quality-of-life impact of nonneoplastic voice disorders: a meta-analysis. Ann Otol Rhinol Laryngol. 2006;115:128–134.
22. Benninger M.S., Ahuja A.S., Gardner G. Assessing outcomes for dysphonic patients. J Voice. 1998;12:540–550.
23. Roy N., Merrill R.M., Gray S.D. Voice disorders in the general population: preva-lence, risk factors, and occupational impact. Laryngoscope. 2005;115:1988–1995.
24. Francis D.O., McKiever M.E., Garrett C.G. Assessment of patient experience with unilateral vocal fold immobility: a preliminary study. J Voice. 2014;28:636–643.
25. Mirza N., Ruiz C., Baum E.D. The prevalence of major psychiatric pathologies in patients with voice disorders. Ear, Nose, Throat J. 2003;82:808–814.
26. Isetti D., Meyer T. Workplace productivity and voice disorders: a cognitive interviewing study on presenteeism in individuals with spasmodic dysphonia. J Voice. 2014;28:700–710.
27. Mendels E.J., Brunings J.W., Hamaekers A.E. Adverse laryngeal effects following short-term general anesthesia: a systematic review. Arch Otolaryngol Head Neck Surg. 2012;138:257–264.
28. Schweiger C., Manica D., Kuhl G. Post-intubation acute laryngeal injuries in infants and children: a new classification system. Int J Pediatr Otorhinolaryngol. 2016;86:177–182.
29. Abaza M.M., Levy S., Hawkshaw M.J. Effects of medications on the voice. Otolaryngol Clin North Am. 2007;40:1081–1090.
30. Verdolini K., Min Y., Titze I.R. Biological mechanisms underlying voice changes due to dehydration. J Speech Lang Hear Res. 2002;45:268–281.
31. Ferreira J., Franco A., Teodoro T. et al. Vernet syndrome resulting from varicella zoster virus infection-a very rare clinical presentation of a common viral infection. J Neurovirol. 2018;24(3):379–381. DOI: 10.1007/s13365-018-0622-8.
32. Bachrach K., Levi J.R., Tracy L.F. Herpes simplex laryngitis: Comparison between pediatric and adult patients. Int J Pediatr Otorhinolaryngol. 2021;142:110596. DOI: 10.1016/j.ijporl.2020.110596.
33. Radzig E.Yu. Voice disorders in children and adolescents and their treatment with the homeopathic drug Gomeovoks. Pediatrics. 2009;88(6):130–136 (in Russ.).
34. On the state of sanitary and epidemiological well-being of the population in the Russian Federation in 2020: State report. Moscow: Federal Service for Surveillance on Consumer Rights Protection and Human Welfare, 2021 (in Russ.).
35. Kallvik E., Toivonen L., Peltola V. et al. Respiratory Tract Infections and Voice Quality in 4-Year-old Children in the STEPS Study. J Voice. 2019;33(5):801.e21–801.e25. DOI: 10.1016/j.jvoice.2018.01.021.
36. Lechien J.R., Chiesa-Estomba C.M., Cabaraux P. et al. Features of Mild-to-Moderate COVID-19 Patients With Dysphonia. J Voice. 1997;20:30183–1. DOI: 10.1016/j.jvoice.2020.05.012.
37. Al-Ani R.M., Rashid R.A. Prevalence of dysphonia due to COVID-19 at Salahaddin General Hospital, Tikrit City, Iraq. Am J Otolaryngol. 2021;42(5):103157. DOI: 10.1016/j.amjoto.2021.103157.
38. Halfpenny R., Stewart A., Carter A. et al. Dysphonia and dysphagia consequences of paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS). Int J Pediatr Otorhinolaryngol. 2021;148:110823. DOI: 10.1016/j.ijporl.2021.110823.
39. Nikolaeva S.V., Zvereva Z.A., Kanner E.V. et al. Clinical and laboratory characteristics of coronavirus infection in children. Infectious diseases. 2018;16(1):35–39 (in Russ.). DOI: 10.20953/1729-9225-2018-1-35-39.
40. Clinical guidelines "Acute laryngitis, diagnosis and treatment". 2016 (in Russ.).
41. Nikiforova G.N., Svistushkin V.M. Possibilities of using complex homeopathic medicines in the treatment and prevention of acute respiratory viral infections. Therapist. 2013;4:91 (in Russ.).
42. Radtsig E.Yu., Degtyareva D.V., Ermilova N.V. Dysphonia in the practice of a pediatrician: causes and methods of treatment. Questions of modern pediatrics. 2013;12(5):123–127 (in Russ.). DOI: 10.15690/vsp.vl2i5.811.
43. Radtsig E.Yu., Ermilova N.V. Voice disorders in different periods of its formation: causes and algorithm of patient management. Russian medical journal. 2016;4:217–220 (in Russ.).
44. Xue S.A., de Schepper L., Нао G.J. Treatment of spasmodic dysphonia with homeopathic medicine: a clinical case report. Homeopathy. 2009;98(1):56–59. DOI: 10.1016/j.homp.2008.11.009.
45. Karneeva O.V., Ryazantsev S.V., Radtsig E.Yu., Kim I.A. Possibilities of clinical homeopathy in the treatment of acute inflammatory diseases of the upper respiratory tract. M., StPb.: Poliforum Group; 2017 (in Russ.).
46. Bogomilskiy M.R., Radzig E.Yu. Laryngitis in children: features of the course and treatment. Otorhinolaryngology Bulletin. 2009;1:45–49 (in Russ.).
47. Stepanova Yu.E., Gotovyakhina T.V., Korneenkov A.A., Koren E.E. Complex treatment of dysphonia in persons of voice-speech professions. Otorhinolaryngology Bulletin. 2017;(3):48–53 (in Russ.).
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