Efficient antiseptic in modern gynecology
Tihomirov A.L.1, Kazenashev V.V.1, Yudina T.A.2
1 Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
2 Multi-specialty medical Holding SM-Clinic, Moscow
Infectious complications prevention currently remains one of the most difficult tasks in gynecology. Antibiotic resistance forces to optimize treatment regimens. Local application of broad-spectrum antiseptics is the most correct trend of infectious complications prevention in gynecological manipulations today. Well known preparations of iodine (in particular its various complexes) are becoming more popular.
The paper reviews povidone iodine's efficacy in prevention and treatment of inflammatory diseases in gynecology. The drug has a wide spectrum of antimicrobial activity, as well as bactericidal, sporicidal and antiviral properties (ie. its spectrum covers Gram-positive and Gram-negative bacteria, fungi, viruses, protozoa, and even prions).
Two forms of production - suppositories and solutions, let it use the drug in different situations: for prevention of pelvic organs inflammatory diseases, in invasive gynecological interventions, infectious complications in obstetrics and for mixed vaginitis management. Combined application of povidone iodine with antibiotics let it reduce the incidence of vulvovaginal candidiasis. In everyday women's life, it is used for prevention of vaginal sexually transmitted infections. The drug is associated with good tolerability profile.
Key words: antiseptics, antibiotics, inflammation, povidone-iodine, mechanism of bactericidal action, antiviral activity, prevention, treatment, efficacy, tolerability.
For citation: Tihomirov A.L., Kazenashev V.V., Yudina T.A. Efficient antiseptic in modern gynecology // RMJ. 2016. № 15. P. 993–996.

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