Role of dietary fiber in correcting microbiota disorders and maintaining immunity

M.D. Ardatskaya

Central State Medical Academy of the Administrative Department of the President of the Russian Federation, Moscow

The article discusses the association between the microbiota and the functioning of individual organs, systems and the entire macroorganism. This interaction is realized at the level of low-molecular-weight metabolites of the intestinal microbiota that can activate, inhibit, modify the processes, functions, and reactions of various organs and systems of the human body. Violation of their qualitative or quantitative ratio is the occurrence and progression factor of many gastrointestinal, metabolic, cardiovascular, hematological, neuropsychiatric, autoimmune and other diseases. The presented volume of reliable clinical data indicates that the prebiotics use, in particular dietary fiber (DF), for the correction of intestinal microbiota disorders is a promising method in the treatment and prevention of various diseases. In turn, partially hydrolyzed guar (cyam opsis) DF (registered in the Russian Federation under the trade name OptiFiber) due to their effects (such as regulating the intestine, reducing abdominal pain, reducing flatus and bloating, increasing the resident intestinal microflora amount and its metabolic activity) helps restore and maintain intestinal eubiosis, normalize the consistency and frequency of stool, relieve symptoms of irritable bowel syndrome, and increase immunity to influenza. At the same time, OptiFiber does not have significant side effects and can be administered for a long-term period in order to supplement the nutrition with the necessary amount of DF.

Keywords: microbiota, short-chain fatty acids (SCFAs), intestinal microbiocenosis, dietary fiber, cyamopsis, immunity, influenza.

For citation: Ardatskaya M.D. Role of dietary fiber in correcting microbiota disorders and maintaining immunity. RMJ. 2020;12:24–29.