Photodynamic therapy with the domestic fluorescent video system of non-muscle invasive bladder cancer

A.B. Babaev¹, O.B. Loran<sup>1,2

1</sup> Russian Medical Academy of Continuous Professional Education, Moscow
² Botkin City Clinical Hospital, Moscow

Non-muscle invasive bladder cancer (NMIBC) is characterized by a continuously progressing current and frequent recurrence. The standard of NMIBC treatment is transurethral resection (TUR), however, the frequency of recurrences after TUR is extremely high, which, in turn, leads to the progression of the tumor process, excluding organ-preserving treatment methods. The problem of detecting this pathology at the initial stage and control of the radicality of the treatment remains extremely important today. At present, physical factors of influence and combinations of physicochemical methods are widely used in diagnostics and treatment of NMIBC patients, allowing selective influence on tumor tissue, one of them is intraoperative performance of photodynamic diagnostics and photodynamic therapy, called “photodynamic teranostics”. However, at the moment there is no assessment of the effectiveness of the domestic fluorescent video system with multispectral laser exposure. This scientific review presents information on the peculiarities of using photodynamic diagnostics and therapy of NMIBC.

Keywords: non-muscle invasive bladder cancer, photodynamic diagnostics, photodynamic therapy, photodynamic teranostics, fluorescent video system, transurethral resection.
For citation: Babaev A.B., Loran O.B. Photodynamic therapy with the domestic fluorescent video system of non-muscle invasive bladder cancer. RMJ. 2019;261:–64.