Modern treatment algorithms of rheumatoid arthritis
Olyunin Yu.A., Nikishina N.Yu.

V.A. Nasonova Research Institute of Rheumatology, Moscow

Treatment approach to rheumatoid arthritis (RA) has undergone dramatic changes in the last decade as a result of the development of novel effective medications and standard algorithms which determine treatment choice in individual cases. These recommendations are based on the “treat-to-target” strategy which was developed on the basis of recent findings and includes major principles of RA treatment. According to the experts, RA treatment goal is the remission or low disease activity. “Treat-to-target” strategy means that disease activity should be measured monthly using one of the RA activity indices until treatment goal (i.e., remission or low inflam-matory activity) is achieved. The prescribed treatment should be corrected at least every 3 months (or every 6 months in stable low disease activity or remission). The achieved treatment goal should be maintained permanently.

Key words: rheumatoid arthritis, treatment, glucocorticoids, disease-modifying anti-rheumatic drugs, engineered biological agents, non-steroidal anti-inflammatory drugs, activity, remission, methotrexate, nimesulide, tumor necrosis factor inhibitors, tofacitinib.

For citation: Olyunin Yu.A., Nikishina N.Yu. Modern treatment algorithms of rheumatoid arthritis // RMJ.  2016. № 26. P. 1765–1771.