Prevention of calcium deficiency in children
DOI: 10.32364/2587-6821-2020-4-8-511-517
T.E. Taranushenko, N.G. Kiseleva
Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky, Krasnoyarsk, Russian Federation
One of the urgent problems of modern pediatrics is to assess the value of adequate calcium intake to ensure the skeleton strength and the formation of tooth resistance to caries in children and adolescents. This article is aimed at providing generalized data on the prevention of calcium deficiency in children and adolescents. The physiology of calcium metabolism and vitamin D regulatory role are discussed. The article describes non-pharmacological and pharmacological methods for the prevention and correction of calcium deficiency in children and adolescents. It also indicates the use of calcium salts in insufficient calcium content in the diet, somatic pathology, as well as with an increase in the need for minerals during periods of intensive growth. The article discusses the differences between organic (citrate, lactate, and calcium gluconate) and inorganic calcium salts (calcium phosphate and carbonate), as well as between liquid and solid forms. The benefi ts of liquid forms should be considered a uniform particle distribution of the active substance, an increase in the surface area of absorption and absorption degree, as well as the possibility of use in children with difficulties in swallowing solid forms. The use of calcium and vitamin D supplements may reduce the risk of adverse events in children.
Keywords: calcium and phosphorus metabolism, bone tissue, calcium, children, adolescents, calcium deficiency, vitamin K, vitamin D.
For citation: Taranushenko T.E., Kiseleva N.G. Prevention of calcium deficiency in children. Russian Medical Inquiry. 2020;4(8):511–517. DOI: 10.32364/2587-6821-2020-4-8-511-517.
Acknowledgement
Editorial Board is grateful to “VTF” Ltd. for the assistance in technical edition of this publication.
About the authors:
Tatyana E. Taranushenko — Dr. of Sci. (Med.), Professor, Head of the Department of Pediatrics, Institute of Postgraduate Education, Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky: 1, Partisana Zheleznyaka str., Krasnoyarsk, 660022, Russian Federation; ORCID iD 0000-0003-2500-8001.
Natalia G. Kiseleva — Cand. of Sci. (Med.), Associate Professor of the Department of Pediatrics, Institute of Postgraduate Education education, Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenetsky: 1, Partisana Zheleznyaka str., Krasnoyarsk, 660022, Russian Federation; ORCID iD 0000-0001-6425-5086.
Contact information: Tatyana E. Taranushenko, e-mail: tetar@rambler.ru. Financial Disclosure: no authors have a financial or property interest in any material or method mentioned. There is no conflict of interests. Received 04.09.2020, revised 19.09.2020, accepted 07.10.2020.
2. Kiseleva N.G., Taranushenko T.E., Golubenko N.K. Diagnosis of osteoporosis in childhood. Meditsinskiy sovet. 2020;(1):186–193. DOI: 10.21518 / 2079-701X-2020-1-186-193 (in Russ.).
3. Calcium deficiency and osteopenic conditions in children, diagnosis, treatment, prevention: scientific and practical program of the Union of Pediatricians of Russia. (Electronic resource). URL: https://www.grweb.su/portfolio/mali/pdf/Ca.pdf (date of access: 26.08.2020) (in Russ.).
4. Cattail V.M., Arches R.A. Pathophysiology of the endocrine system. SPb. — M.: Nevsky dialect — Publishing house Binom; 2001.
5. Guidelines for Pediatric Endocrinology. Ed. I.I. Dedova, V.A. Peterkova. Moscow: Universum Publishing; 2006 (in Russ.).
6. Guidelines for Pediatric Endocrinology. Ed. Charles G.D. Brooke, Rosalind S. Brown: Trans. from English. Ed. V.A. Peterkova. M.: GEOTAR-Media; 2009 (in Russ.).
7. Handbook of a pediatric endocrinologist. I.I. Dedov, V.A. Peterkova. 3rd ed., Rev. and finished. M.: Literra; 2020.
8. Klyuchnikov S.O., Kravchuk D.A., Hovhannisyan M.G. Osteoporosis in children and its relevance for pediatric sports medicine. Rossiyskiy vestnik perinatologii i pediatrii. 2017;62(3):112–120. DOI: 10.21508/1027-4065-2017-62-3-112-120 (in Russ.).
9. Maltsev S.V., Mansurova G.Sh. Decreased bone mineral density in children and adolescents: causes, frequency of development, treatment. Voprosy sovremennoy pediatrii. 2015;14(5):573–578. DOI: 10.15690/vsp.v14i5.1442 (in Russ.).
10. Physiology of growth and development of children and adolescents (theoretical and clinical issues): in 2 volumes. Ed. A.A. Baranov, L.A. Scheplyagina. 2nd ed., Rev. and add. M.: GEOTAR-Media; 2006 (in Russ.).
11. Alekseeva I.A. Assessment of caries resistance of dental hard tissues and the state of phosphorus-calcium metabolism in adolescents: thesis. M., 2014 (in Russ.).
12. Kiselnikova L.P., Alekseeva I.A., Scheplyagina L.A. Evaluation of calcium provision in adolescent children with high caries activity. Rossiyskaya stomatologiya. 2013;2:31–34 (in Russ.).
13. Ippolitov Yu.A., Plotnikova Ya.A., Alyoshina E.O., Markina T.V. The use of mineral complexes in endogenous and exogenous methods of prevention in order to prevent the development of primary demineralization of dental hard tissues. Vestnik novykh meditsinskikh tekhnologiy. 2016;23(2):164–170. DOI: 10.12737 / 20443 (in Russ.).
14. Taranushenko T.E., Kiseleva N.G. Osteoporosis in childhood: features of skeletal mineralization in children, prevention and treatment. Meditsinskiy sovet. 2020;10:164–171. DOI: 10.21518/2079-701X-2020-10-164-171 (in Russ.).
15. Osteoporosis. Ed. O.M. Lesnyak, L.I. Benevolenskaya. 2nd ed., Rev. and add. M.: GEOTAR-Media; 2010 (in Russ.).
16. National program to optimize the provision of vitamins and minerals for children in Russia. M.: Pediatr; 2017 (in Russ.).
17. Shcheplyagina L.A., Samokhina E.O., Sotnikova E.N., Kruglova I.V. Efficiency of food prevention of growth disorders in preschool age. Pediatriya. 2008;87(3):68–72 (in Russ.).
18. Dydykina I.S., Dydykina P.S., Alekseeva O.G. The contribution of trace elements (copper, manganese, zinc, boron) to bone health: issues of prevention and treatment of osteopenia and osteoporosis. Effektivnaya farmakoterapiya. 2013;38:42–49 (in Russ.).
19. Zakharova I.N., Tvorogova T.M., Vorob’eva A.S., Kuznetsova O.A. Microelementosis as a factor in the formation of osteopenia in adolescents. Pediatriya. 2012;91(1):67–75 (in Russ.).
20. Shcheplyagina L.A., Chibrina E.V., Rimarchuk G.V. et al. Efficacy of the combined calcium and D3 preparation in children with decreased bone strength. Practical issues of pediatrics. 2009;4(4):20–23 (in Russ.).
21. Osteoporosis. Clinical guidelines. (Electronic resource) URL: https://rae-org.ru/system/files/documents/pdf/kr_op_24.12.2019.pdf (access date: 26.08.2020) (in Russ.).
22. Gromova O.A., Torshin I.Yu., Pronin A.V. et al. Differentiated approach to the choice of second-generation soluble calcium preparations. Lechashchiy vrach. 2014;11:60–65 (in Russ.).
23. National program "Vitamin D deficiency in children and adolescents of the Russian Federation: modern approaches to correction". M.: Pediatr; 2018 (in Russ.).
24. Korovina N.A., Tvorogova T.M., Gavryushova L.P., Vorobieva A.S. Safety criteria for calcium supplements for the prevention of osteopenia in adolescents. Pediatriya. 2006;5(14):81–86 (in Russ.).
25. Combs G.F. The vitamins: fundamental aspects in nutrition and health. Academic Press; 1998.

This work is licensed under a Creative Commons «Attribution» 4.0 License.
















