Russian Medical Inquiry
(RMZh. Meditsinskoe Obozrenie) ISSN 2587-6821 (Print), 2686-9918 (Online)

The onset of axial spondylitis against the background of Reiter’s syndrome (a clinical case)

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N.A. Besedovskaya1,2, A.I. Zagrebneva1,2

1 Municipal Clinical Hospital № 52, Moscow
2 Pirogov Russian National Research Medical University, Moscow

Reactive arthritis (ReA) is a sterile inflammatory disease of the musculoskeletal system, induced by infections of extraarticular localization, especially the genitourinary or intestinal tract, which is part of the group of seronegative spondyloarthropathies (SS). A set of symptoms, including urethritis, arthritis, conjunctivitis , is called the “oculo-urethro-synovial syndrome” or “Reiter’s syndrome”.
The article describes a clinical case of the onset of ankylosing spondylitis developed against a background of acute chlamydial infection, “oculo-urethro-synovial syndrome”. The presence of sarroiliitis according to MRI, pain in the lower back of the inflammatory character, peripheral arthritis, achillitis, stiffness, uveitis, developed in dynamics, positive HLA-B27 antigen, incomplete effectiveness of antibiotic therapy, a positive effect of the NSAIDs and GC therapy, were the basis for diagnosing the patient with axial spondylitis against the background of Reuter’s syndrome of chlamydial etiology. This clinical case is indicative of the complexity of diagnosis, the difficulty in selecting therapy if patients have a combination of the infectious process in the debut and the immune process over time.

Key words: reactive arthritis, spondyloarthritis, ankylosing spondylitis, septic variant, Reiter’s syndrome.
For citation: BesedovskayaN.A., Zagrebneva A.I. The onset of axial spondylitis against the background of Reiter’s syndrome (a clinical case) // RMJ. Medical Review. 2018. № 5. P. 43–45.
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