Optimization of therapy for deficiency conditions and asthenia in pediatric practice

Evelina E. Lokshina¹, Tatiana. I. Rychkova¹, Natalia K. Shumeiko¹, Irina I. Khmelkova²

1. FSBEI HE "ROSUNIMED" OF MOH OF RUSSIA; 4, Dolgorukovskaya St., Moscow, 127006, Russia

2. Children’s State Hospital of St Vladimir; 1/3, Rubtsovsko-Dvortsovaya St., Moscow, 107014, Russia

In recent decades, specialists have widely discussed the role of deficiency conditions, including deficiency of various micronutrients, as the cause of a wide range of diseases. Particular attention is paid to choline. Choline is necessary for the proper functioning of the liver, muscles and brain, lipid metabolism and maintenance of the phospholipid composition of membranes of all types of cells. Insufficient choline content in the diet can affect cognitive abilities, lead to memory loss in a child, and increase the risk of cardiovascular and metabolic disorders. According to various studies, asthenia of varying severity is detected in 12-50% of children, most often in preschool and school age. Symptoms of asthenia include weakness, fatigue, sleep disturbances, increased irritability, muscle and headaches and some other symptoms. Post-infectious asthenia after acute respiratory disease and new coronavirus infection (post-covid syndrome), as well as asthenia due to multitasking in schoolchildren are a pressing problem in pediatric practice. Asthenia worsens health and disrupts social adaptation. The use of the complex choline-containing dietary supplement Kidz (Kidz) syrup with choline leads to a decrease in asthenia symptoms, increased resistance to psychoemotional experiences, improved cognitive functions, and the ability to cope with increased mental stress.

Key words: deficiency, choline, asthenia, Kidz choline syrup