Renocardiac syndrome in a child with non-inherited connective tissue disease
DOI: 10.32364/2618-8430-2021-4-2-184-188
N.S. Cherkasov, O.V. Davydova, L.I. Derbeneva, Yu.A. Lutsenko
Astrakhan State Medical University, Astrakhan, Russian Federation
This paper describes a case report of renocardiac syndrome in a child with non-inherited connective tissue disease (CTD). The importance of CTD is accounted for by its high occurrence (up to 80%) and controversial interpretation of phenotypic and visceral signs. In children, combined diseases more commonly develop under the effects of similar pathogenic factors or one disease impacts the development of another one. It was demonstrated that five organ systems are affected in 20% of children with CTD and three organ systems are affected in 40% of children with CTD. The most common conditions are cardiovascular and osteoarticular disorders followed by gastrointestinal disorders. Musculoskeletal and urinary tract disorders occurred in 33% and 19.5%, respectively. Renocardiac syndrome is of particular interest from the viewpoint of comorbidity. This case report addresses renocardiac syndrome in a 6-year-old boy. Eight phenotypic and six visceral signs of CTD were identified in this child. Cardiac and renal abnormalities prevailed among internal signs. Therefore, CTD plays an important role in the development of renocardiac syndrome.
Keywords: connective tissue disease, renocardiac syndrome, children, heart, kidney, comorbidity.
For citation: Cherkasov N.S., Davydova O.V., Derbeneva L.I., Lutsenko Yu.A. Renocardiac syndrome in a child with non-inherited connective tissue disease. Russian Journal of Woman and Child Health. 2021;4(2):184–188. DOI: 10.32364/2618-8430-2021-4-2-184-188.
About the authors:
Nikolay S. Cherkasov — Doct. of Sci. (Med.), Рrofessor of the Department of Hospital pediatrics with the Course of Postgraduate Education, Astrakhan State Medical University; 121, Bakinskaya str., Astrakhan, 414000, Russian Federation; ORCID iD 0000-0001-9532-5446.
Oksana V. Davydova — Cand. of Sci. (Med.), associate professor of the Department of Hospital pediatrics with the Course of Postgraduate Education, Astrakhan State Medical University; 121, Bakinskaya str., Astrakhan, 414000, Russian Federation; ORCID iD 0000-0001-5616-7342.
Larisa I. Derbeneva — Cand. of Sci. (Med.), associate professor of the Department of Hospital pediatrics with the Course of Postgraduate Education, Astrakhan State Medical University; 121, Bakinskaya str., Astrakhan, 414000, Russian Federation; ORCID iD 0000-0002-5416-9042.
Yuliya A. Lutsenko — postgraduate student of the Department of Hospital pediatrics with the Course of Postgraduate Education, Astrakhan State Medical University; 121, Bakinskaya str., Astrakhan, 414000, Russian Federation; ORCID iD 0000-0001-6336-7887.
Contact information: Oksana V. Davydova, e-mail: oksada2009@yandex.ru. Financial Disclosure: no authors have a financial or property interest in any material or method mentioned. There is no conflict of interests. Received 04.03.2021, revised 21.03.2021, accepted 15.04.2021.
2. Nechaeva G.I., Yakovlev V.M., Konev V.P. et al. Connective tissue dysplasia: major clinical syndromes, the wording of the diagnosis, treatment. Lechashchiy vrach. 2008;2:22–28 (in Russ.).
3. Abbakumova L.N., Arsentyev V.G., Gnusaev S.F. et al. Multifactorial and hereditary connective tissue disorders in children. Diagnostic algorithms. Management tactics. Russian guidelines. Pediatr. 2016;7(2):5–39 (in Russ.).
4. Arsentiev V.G., Sereda Yu.V., Tikhonov V.V. et al. Connective tissue dysplasia is the constitutional basis of multiple organ disorders in children and adolescents. Pediatriya. 2011;5(90):54–57 (in Russ.).
5. Mutalov A.G. Comorbid pathology in the practice of a pediatrician-features of diagnosis and management tactics. (Electronic resource.) URL: https://medvestnik.ru/content/medarticles (access date: 18.02.2021) (in Russ.).
6. Artamonov R.G. On the issue of comorbidity in Pediatrics. Pediatriya. 2012;4(91):146–149 (in Russ.).
7. Davydova O.V., Cherkasov N.S., Makukhina L.P. et al. Comorbid pathology in infants born with low and very low birth weight. Astrakhanskiy meditsinskiy zhurnal. 2015;4:50–57 (in Russ.).
8. Lutsenko Yu.A., Cherkasov N.S., Davydova O.V. et al. Clinical and instrumental assessment of forms and syndromes undifferentiated connective tissue dysplasia in children. Vestnik Volgogradskogo gosudarstvennogo meditsinskogo universiteta. 2019;3(71):58–61 (in Russ.).
9. Nechaeva G.I., Loginova E.N., Tsukanov A.Yu. et al. Kidney pathology in connective tissue dysplasia: an interdisciplinary approach. Lechashchiy vrach. 2016;1:54–57 (in Russ.).
10. Zueva T.V., Zhdanova T.V., Uraslina S.E. Comorbidity of renal and cardiac pathology. Meditsinskiy vestnik Severnogo Kavkaza. 2019;4(14):711–715 (in Russ.). DOI: 10.14300/mnnc.2019.14178.
11. Erman M.V., Pervunina T.M. Cardiorenal continuum in children (literature review). Vestnik Sankt-Peterburgskogo universiteta. 2012;2(11):53–57 (in Russ.).
12. Aksenova M.E. Cardiovascular system diseases in children with chronic kidney diseases: Epidemiology, risk factors, pathogenesis. Rossiyskiy vestnik perinatologii i pediatrii. 2015;2:22–28 (in Russ.).
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