Substantiation of energotropic therapy of vegetative disorders in children
E. V. Neudakhin

Scientific and practical center for specialized medical care for children named after V. F. Voino-Yasenetskiy

The article presents information on the terminology of vegetative disorders. It shows the expediency of using the term «syndrome of vegetative dystonia», which is a complex of symptoms caused by violation of autonomic regulation of all organs and systems of the organism, metabolic processes as a result of primary or secondary morphofunctional changes in the suprasegmentary and / or segmental structures of the autonomic nervous system, combined with psychoemotional disorders. The pathogenesis of vegetative disorders is considered from the viewpoint of alternative interaction of the processes forming adaptive-compensatory reactions in the body. It is demonstrated that the pathogenesis of the syndrome of vegetative dystonia is caused by the imbalance between the sympathetic and parasympathetic regulation of the organs and systems of the organism, connected with the disintegration of the higher vegetative centers. The mechanisms of action of energotropic drugs (L-carnitine and coenzyme Q10) are described in detail, information on the effectiveness of their use for various manifestations of vegetative disorders is presented. Data from the literature indicate a pronounced energotropic and vegetotropic action of these drugs. The discussed drugs are systemic drugs, which corresponds to the systemic nature of autonomic regulation. The positive effect of their action is associated, first of all, with their participation in the energy supply of all organs and systems of the body.

Key words: children, vegetative dystonia, L-carnitine, coenzyme Q10, alternative interaction.
For citation: Neudakhin E. V. Substantiation of energotropic therapy of vegetative disorders in children // RMJ. 2018. № 2(II)P. 107–112.