Possibilities of topical etiotropic drugs in the treatment of patients with acute tonsillopharyngitis
V.M. Svistushkin, G.N. Nikiforova, L.A. Toporkova, O.Yu. Karpova 

Sechenov University, Moscow

Acute tonsillopharyngitis is a general term used to describe any acute inflammation of the mucous membrane and oropharynx lymphoid formations. Administration of topical drugs (mouthwashes, sprays, lozenges) is the main treatment method for most patients with inflammatory pathology and streptococcal tonsillopharyngitis. Most often, local dosage forms are represented by a combination of various drugs, which helps them to quickly and effectively interact on the main manifestations of the disease.
The article highlights the possibility of using local antibacterial and antiseptic drugs for the topical treatment of acute tonsillopharyngitis. Data are given on the use of the drug Grammidin^®, based on a local broad-spectrum antibiotic gramicidin S and antiseptic cetylpyridinium chloride. The drug showed high efficacy and safety of use in adults and children, due to the combination of active substances and their synergism. The strength of the drug Grammidin^® is in its effectiveness against microbial associations — biofilms, which is confirmed, in particular, with data on the use of the drug in patients with exacerbation of chronic infectious-inflammatory diseases of the oropharynx. Grammidin^® in the pharmaceutical form of «metered dose spray» provides additional benefits in the treatment of patients with infectious and inflammatory diseases of the pharynx.

Key words: acute tonsillopharyngitis, microbial associations, metered dose spray, gramicidin S, cetylpyridinium chloride, Grammidin^®.
For citation: Svistushkin V.M., Nikiforova G.N., Toporkova L.A., Karpova O.Yu. Possibilities of topical etiotropic drugs in the treatment of patients with acute tonsillopharyngitis // RMJ. 2018. № 10(II). P.97 –102.