Russian Medical Inquiry
(RMZh. Meditsinskoe Obozrenie) ISSN 2587-6821 (Print), 2686-9918 (Online)

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Malignant ovarian tumors in pregnant women

Yu.E. Dobrokhotova, Yu.G. Payanidi, E.I. Borovkova, K.V. Morozova, E.A. Nagaytseva, A.M. Arutyunyan


Pirogov Russian National Research Medical University, Moscow


The article presents the data systematic analysis results, available in the modern literature concerning the pregnant women management with ovarian cancer (OC). Diagnosis difficulties are associated with physiological gestational processes. All cases of mass lesions manifestation in the ovaries require thorough dynamic observation, additional survey techniques (in particular, MRI performance), and in some cases — surgical treatment. Surgical staging followed by chemotherapy is indicated for pregnant women with OC. In cases of advanced OC, chemotherapy may be the only treatment option to maintain pregnancy. Chemotherapy is not indicated for pregnant women with non-epithelial ovarian tumors of the early stages. In far-advanced stages of OC, chemotherapy is carried out in the same way as in non-pregnant women. In OC and pregnancy, obstetric complications can be caused not only by the underlying disease  but also by complications caused by surgical treatment and chemotherapy. The article presents the clinical cases of pregnant women management with OC.

Keywords: malignant ovarian tumors, pregnancy, cyst torsion, chemotherapy, cytoreductive surgery.

For citation: Dobrokhotova Yu.E., Payanidi Yu.G., Borovkova E.I. et al. Malignant ovarian tumors in pregnant women. RMJ. 2019;6:45–52.



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