Brain metastases, modern treatment standards
Banov C.M.¹, Golanov A.V.¹, Zaitsev A.M.², Bekyashev A.Kh.³, Vetlovana E.R.¹, Durgaryan A.A.<sup>1

1</sup> National Medical Research Center Of Neurosurgery named after Academic N.N. Burdenko, Moscow
² Moscow Scientific Oncological Institute named after P.A. Herzen, Moscow
³ National Medical Research Center of Oncology named after N.N. Blokhin, Moscow

The development of chemotherapy has led to significant progress in the therapy of malignant tumors, but its effectiveness against brain metastases remains insufficient. Fractional whole brain radiotherapy, surgical treatment and radiosurgery are the standard methods of treating patients with brain metastases.
Improving the methods of neuroimaging, the introduction into clinical practice of the principles of microsurgery and radiosurgery with the use of the Gamma-knife and Cyber-knife devices has significantly changed the results of treatment of patients with brain metastases, which allowed to formulate new principles for the treatment of this group of patients.
This review summarizes the available methods for treating patients with brain metastases, with an emphasis on overall survival, local control, distant metastases, quality of life, and the potential for potential combinations of existing treatments. The article shows that personalized approaches in the treatment of patients with brain metastases are optimal and improve the results of treatment.

Key words: brain metastases, radiosurgery, microsurgery, whole brain radiotherapy. 
For citation: Banov C.M., Golanov A.V., Zaitsev A.M. et al. Brain metastases, modern treatment standards // RMJ. 2017. № 16. P. 1181–1185.