Hodgkin lymphoma in pregnant women: patient management
DOI: 10.32364/2618-8430-2023-6-4-11
Yu.E. Dobrokhotova1, S.Zh. Danelian2, E.I. Borovkova1, E.A. Nagaytseva2, D.Kh. Sarakhova2, I.M. Borovkov3, M.S. Guseva4
1Pirogov Russian National Research Medical University, Moscow, Russian Federation
2Moscow Multidisciplinary Clinical Center "Kommunarka", Moscow, Russian Federation
3N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russian Federation
4V.V. Veresaev City Clinical Hospital, Moscow, Russian Federation
Hodgkin lymphoma (HL) is a B-cell malignant lymphoproliferative disease occurring with a prevalence of 2.2 cases per 100,000 population per year, more commonly in women, with a peak incidence in the range of 16–35 years. The most common type in pregnant women is classical HL, diagnosed with a prevalence of 1:1000–1:6000. The authors present a literature review on pregnancy in patients with HL, as well as describe own experience of delivery in 20 patients with HL, of whom 16 (80%) had the disease in stable remission, and 4 (20%) were first diagnosed with HL during pregnancy. The pregnancy course was complicated by preeclampsia in 4 (20%) patients, threatened preterm labor in 5 (25%) and anemia in 6 (30%). Delivery at term occurred in 18 (90%), by cesarean section in 4 (20%).
Keywords: Hodgkin lymphoma, lymphogranulomatosis, pregnancy, lymphadenopathy, polychemotherapy, radiation therapy.
For citation: Dobrokhotova Yu.E., Danelian S.Zh., Borovkova E.I., Nagaytseva E.A., Sarakhova D.Kh., Borovkov I.M., Guseva M.S. Hodgkin lymphoma in pregnant women: patient management. Russian Journal of Woman and Child Health. 2023;6(4):391–398 (in Russ.). DOI: 10.32364/2618-8430-2023-6-4-11.
About the authors:
Yulia E. Dobrokhotova — Dr. Sc. (Med.), Professor, Head of the Department of Obstetrics and Gynecology, Pirogov Russian National Research Medical University; 1, Ostrovityanov str., Moscow, 117997, Russian Federation, ORCID iD 0000-0002-7830-2290.
Sonya Zh. Danelyan — C. Sc. (Med.), Deputy Chief Medical Officer of Obstetrics and Gynecology, Moscow Multidisciplinary Clinical Center "Kommunarka"; 8, Sosneskii stan, Kommunarka settlement, Sosenskoe settlement, Moscow, 108814, Russian Federation; ORCID iD 0000-0002-8594-6406.
Ekaterina I. Borovkova — Dr. Sc. (Med.), Associate Professor, Professor of the Department of Obstetrics and Gynecology, Pirogov Russian National Research Medical University; 1, Ostrovityanov str., Moscow, 117997, Russian Federation, ORCID iD 0000-0001-7140-262X.
Elena A. Nagaytseva — C. Sc. (Med.), Head of the Department of Diagnostic Ultrasound of the Maternity Hospital, Moscow Multidisciplinary Clinical Center "Kommunarka"; 8, Sosneskii stan, Kommunarka settlement, Sosenskoe settlement, Moscow, 108814, Russian Federation.
Jamilya Kh. Sarakhova — C. Sc. (Med.), Head of the Department of Pregnancy Pathology of the Maternity Hospital, Moscow Multidisciplinary Clinical Center "Kommunarka"; 8, Sosneskii stan, Kommunarka settlement, Sosenskoe settlement, Moscow, 108814, Russian Federation.
Ivan M. Borovkov — oncologist, postgraduate student of the Department of Postgraduate Medical Education, N.N. Blokhin National Medical Research Center of Oncology; 23, Kashirskoye highway, Moscow, 115478, Russian Federation; ORCID iD 0000-0002-2017-8047.
Marina S. Guseva — obstetrician-gynecologist, V.V. Veresaev City Clinical Hospital; 10, Lobnenskaya str., Moscow, 127644, Russian Federation; ORCID iD 0000-0003-4653-2208.
Contact information: Ekaterina I. Borovkova, e-mail: Katyanikitina@mail.ru.
Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.
There is no conflict of interest.
Received 15.09.2023.
Revised 07.10.2023.
Accepted 28.10.2023.
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