Burkitt’s lymphoma and pregnancy. Advantages of today’s medicine
DOI: 10.32364/2618-8430-2020-3-3-211-216
T.S. Kotomina, E.A. Baryakh, E.N. Misyurina, E.I. Zhelnova, I.Yu. Kokoya, V.M. Grabovskiy, M.A. Lysenko
City Clinical Hospital No. 52, Moscow, Russian Federation
Recent years have seen the increase in the rate of childbirth after the age of 30 years. This is associated with higher risks for a mother and a child as well as higher rate of cancers diagnosed during pregnancy including non-Hodgkin’s lymphoma (NHL). The data on pregnancy-associated NHLs are limited by individual case studies. This makes difficult to develop a therapeutic strategy for lymphoma and pregnancy management in women with hematologic malignancies. The paper addresses the case study of a rare combination of Burkitt’s lymphoma and pregnancy. At 20 weeks of the pregnancy, right ovarian tumor was identified by magnetic resonance imaging. Burkitt’s lymphoma was verified by the biopsy of the excised ovary. Progressive tumor growth required chemotherapy. R-DA-EPOCH chemotherapy program was successful and also allowed for pregnancy prolongation and led to favorable perinatal outcome.
Keywords: pregnancy, Burkitt’s lymphoma, non-Hodgkin’s lymphoma, chemotherapy, remission, adnexectomy.
For citation: Kotomina T.S., Baryakh E.A., Misyurina E.N. et al. Burkitt’s lymphoma and pregnancy. Advantages of today’s medicine. Russian Journal of Woman and Child Health. 2020;3(3):211–216. DOI: 10.32364/2618-8430-2020-3-3-211-216.
About the authors:
Tat’yana S. Kotomina — Cand. of Sci. (Med.), Head of the Maternity Department, Branch of the City Clinical Hospital No. 52, 11, Sosnovaya str., Moscow, 123182, Russian Federation, ORCID iD 0000-0002-5660-2380.
Elena A. Baryakh — Doct. of Sci. (Med.), Head of the Department of Hematology and Chemotherapy, City Clinical Hospital No. 52, 3, Pekhotnaya str., Moscow, 123182, Russian Federation, ORCID iD 0000-0001-6880-9269.
Elena N. Misyurina — Cand. of Sci. (Med.), Head of the Hematological Service, City Clinical Hospital No. 52, 3, Pekhotnaya str., Moscow, 123182, Russian Federation, ORCID iD 0000-0003-2419-4850.
Evgeniya I. Zhelnova — Cand. of Sci. (Med.), Head of the Department of Hematology and High-Dose Chemotherapy, City Clinical Hospital No. 52, 3, Pekhotnaya str., Moscow, 123182, Russian Federation, ORCID iD 0000-0002-0343-9348.
Inga Yu. Kokaya — Cand. of Sci. (Med.), Head of the Maternity Department, Branch of the City Clinical Hospital No. 52, 11, Sosnovaya str., Moscow, 123182, Russian Federation, ORCID iD 0000-0002-0637-1537.
Vasiliy M. Grabovskiy — Deputy Head Doctor for Obstetrical Gynecological Service, Branch of the City Clinical Hospital No. 52, 11, Sosnovaya str., Moscow, 123182, Russian Federation, ORCID iD 0000-0002-7048-4827.
Mar’yana A. Lysenko — Doct. of Sci. (Med.), Head Doctor, City Clinical Hospital No. 52, 3, Pekhotnaya str., Moscow, 123182, Russian Federation, ORCID iD 0000-0001-6010-7975.
Contact information: Tat’yana S. Kotomina, e-mail: tatakotomina@mail.ru. Financial Disclosure: no authors have a financial or property interest in any material or method mentioned. There is no conflict of interests. Received 23.01.2020, revised 06.02.2020, accepted 20.02.2020.
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