Pregnancy outcomes of female childhood cancer survivors

D.N. Kurochkina¹, S.A. Kuleva²

¹ St. Petersburg Clinical Scientific and Practical Center of Specialized Medical Care (Oncological), St. Petersburg

² National Medical Research Center of Oncology named after N.N. Petrov, St. Petersburg

The article provides an analysis of literature about pregnancy outcomes in female childhood cancer survivors. Thanks to modern advances in the therapy of malignant tumors in children, the majority of patients reach reproductive age. In women cured of childhood malignant tumors, the risks of complications of pregnancy and childbirth, miscarriage in early pregnancy, intrauterine growth retardation and fetal development, gestational diabetes, hypertension, preterm labor, anemia, uterine rupture during labor, significantly increase. For children born from such mothers, lower birth weight, higher incidence of congenital malformations, higher incidence of stillbirths are characteristic. In order to timely detect abnormalities during pregnancy and fetal development abnormalities, careful monitoring of pregnant women who underwent treatment for malignant tumors in childhood is necessary. They require increased attention during the planning and management of their pregnancy and labor, and the ir born children must be carefully examined for the presence of stigma of disembryogenesis and malformations. A special group consists of children with a family «cancer» history, which should be observed from birth to old age with a frequency of once a year.

Keywords: pregnancy, malignant tumors, children, fertility.

For citation: Kurochkina D.N., Kuleva S.A. Pregnancy outcomes of female childhood cancer survivors. RMJ. 2019;6:53–56.