Russian Medical Inquiry
(RMZh. Meditsinskoe Obozrenie) ISSN 2587-6821 (Print), 2686-9918 (Online)

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Current approaches to prevention and treatment of secondary dry eye syndrome
Egorov E.A., Romanova T.B., Rybakova E.G., Oganezova J.G.

N.I. Pirogov Russian National Research Medical University, Moscow

The article describes the most common diseases and conditions with complications in the form of «dry eye» syndrome (DES) or secondary «dry eye.» In primary open-angle glaucoma the DES incidence depends on the clinical type of the disease, the age, the use of 3 or more drugs with local hypotensive action. The severity of the DES is directly related to the duration of glaucoma, the use of the drops containing benzalkonium chloride. Dysfunction of the meibomian glands and blepharitis are the reasons for the development of lipid dependent DES. Reducing the content of lipids in the tear film, thinning the surface layer, evaporation of the aqueous fraction of tears and increasing tear osmolarity causes eye inflammation, i.e. the blepharitis of various etiologies. Treatment of such patients should be comprehensive. The common approach in the «dry eye» prevention and treatment in all of these groups of patients is the use of artificial tears with hyaluronic acid. The article describes the effectiveness of preservative-free drugs: HYLO-СOMOD®, HYLOMAX-СOMOD®, HYLOSAR СOMOD® and HYLOPARIN СOMOD® («URSAFARM Arzneimittel GmbH», Germany).

Key words: «dry eye», tear film, antiglaucoma drops, preservatives, meibomian gland dysfunction, sodium hyaluronate, artificial tears 
For citation: Egorov E.A., Romanova T.B., Rybakova E.G., Oganezova J.G. Current approaches to prevention and treatment of secondary dry eye syndrome // RMJ. Clinical ophthalmology. 2017. № 1. P. 61–64.

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