Hyaluronic acid as a component of tear substitutes
Egorov A.E.^1,2, Eliseeva T.O.<sup>1,2

1</sup> Municipal Clinical Hospital 15 named after O.M. Filatov, Moscow
² Russian National Research Medical University named after N.I. Pirogov, Moscow

During the last years tear substitutes have been considered as a basic medicamental treatment for the dry eye syndrome. Their effect is directed to compensation of watery component of the tear and increase of the tear film stability. Focus is made on hyaluronic acid, its main characteristics, mechanism of its action and its effect in different concentrations. Data of clinical and preclinical studies that state the advantages of hyaluronic acid as the component of tear substitute are discussed. Characteristics of the Vismed product range is described in terms of its correspondence with recommendations for the “ideal” tear substitute content. They include hyaluronic acid, electrolytes and are hypotonic ophthalmic solutions. Because of these properties they are maintaining prolonged wetting and protective effect on the eye tissues. The risk of eye cells damage, eye diseases is decreased and the level of the compliance is higher.

Key words: hyaluronic acid, dry eye syndrome, viscoelastic properties, osmolarity.

For citation: Egorov A.E., Eliseeva T.O. Hyaluronic acid as a component of tear substitutes // RMJ. Clinical ophthalmology. 2016. № 4. P. 224–226.