Treatment of a patient with allergic conjunctivitis: recommendations to the outpatient ophthalmologist
Egorov A.E., Zakharova M.A.

Russian National Research Medical University named after N.I. Pirogov, Moscow

In the pathogenesis of allergic diseases, in particular allergic conjunctivitis (AС), a key role is played by histamine and histamine Н1-receptors. Therefore, it is generally accepted that Н1-receptor antagonists are drugs of the first choice in the treatment of allergies. Preparations of this group are highly effective, well tolerated, their therapeutic effect begins within the first minutes after instillation, they have a convenient instillation regimen and have almost no side effect. One of the representatives of this group of drugs for the treatment of acute allergic conjunctivitis is azelastine, which is a highly specific antagonist of Н1-receptors of the second generation. In the presented studies, azelastine showed good tolerability and high therapeutic efficacy, the effect of the drug begins in 3 minutes after instillation and lasts for a long time, which allows to use it twice a day. The article shows the efficacy of azelastine eye drops which exceeds the efficacy of placebo, cromoglicate and levocabastine drops. The clinical efficacy of azelastine monotherapy in the treatment of various allergic conjunctivitis has been proved, as well as its effectiveness in the treatment regimens of acute infectious conjunctivitis.

Key words: allergic conjunctivitis, azelastine, Allergodyl, eye drops.
For citation: Egorov A.E., Zakharova M.A. Treatment of a patient with allergic conjunctivitis: recommendations to the outpatient ophthalmologist // RMJ. Clinical ophthalmology. 2017. № 2. P. 111–114.