Diagnosis of X-ray negative intraocular foreign bodies
DOI: 10.32364/2311-7729-2025-25-2-7
A.S. Chernakov1, G.Sh. Arzhimatova1,2, A.D. Rumiantsev1, N.S. Ryazantsev1
1Botkin Hospital, Moscow, Russian Federation
2Russian Medical Academy of Continuous Professional Education, Moscow,
Russian Federation
The paper is focused on diagnosis of X-ray negative intraocular foreign bodies (IOFB) made of wood, plastic, and glass that require a special diagnostic technique. The main IOFB imaging methods (computed tomography [CT], considered as the "gold standard" of diagnosis, magnetic resonance imaging [MRI], ultrasonography [US] and radiography) are addressed. Although CT provides high sensitivity (up to 100% for metals) due to slice thickness (from 0.5 mm), it is less efficient to detect wooden and plastic IOFB. In these cases, CT should be combined with MRI and US. Even as MRI is an efficient method to detect organic materials, absence of metallic IOFB should be confirmed before a start of the investigation. US is a versatile technique, but it depends on a physician's skills and its application is limited in persons with open eye injuries. As radiography yields little information, it is used in the absence of CT only. As for the clinical case report, radiography and US failed to detect an IOFB in a patient with a penetrating eye injury. Nevertheless, it was revealed by CT. Vitrectomy followed by exploration of the vitreal cavity provided IOFB removal and appropriate retinal adaptation. The clinical case report highlights a need for a comprehensive diagnostic technique with a priority of CT combined with MRI and US to detect non-metallic IOFB.
Keywords: eye injury, intraocular foreign body, computed tomography, radiography, magnetic resonance imaging, ultrasonography.
For citation: Chernakov A.S., Arzhimatova G.Sh., Rumiantsev A.D., Ryazantsev N.S. Diagnosis of X-ray negative intraocular foreign bodies. Russian Journal of Clinical Ophthalmology. 2025;25(2):124–130 (in Russ.). DOI: 10.32364/2311-7729-2025-25-2-7
ABOUT THE AUTHORS:
Alexander S. Chernakov — Ophthalmologist of MCOC, Botkin Hospital; 5, 2nd Botkinskiy pass., Moscow, 125284, Russian Federation; ORCID iD 0009-0008-8536-0553
Gulzhiyan Sh. Arzhimatova — C. Sc. (Med.), Head of of MCOC, Botkin Hospital; 5, 2nd Botkinskiy pass., Moscow, 125284, Russian Federation; Assistant Professor of the Department of Ophthalmology, Russian Medical Academy of Continuous Professional Education; build. 1, 2/1, Barrikadnaya str., Moscow, 125993, Russian Federation; ORCID iD 0000-0001- 9080-3170
Alexander D. Rumiantsev — C. Sc. (Med.), Ophthalmologist, of MCOC, Botkin Hospital; 5, 2nd Botkinskiy pass., Moscow, 125284, Russian Federation; ORCID iD 0009-0000-9454- 4786
Nikita S. Ryazantsev — Ophthalmologist of MCOC, Botkin Hospital; 5, 2nd Botkinskiy pass., Moscow, 125284, Russian Federation; ORCID iD 0009-0007-3259-835X
Contact information: Alexander S. Chernakov, e-mail: doctor-chernakov@yandex.ru
Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.
There is no conflict of interest.
Received 12.03.2025.
Revised 04.04.2025.
Accepted 29.04.2025.
2. Социально значимые заболевания населения России в 2018 году (статистические материалы). Под ред. Александровой Г.А., Голубева Н.А., Тюриной Е.М. и др. ЦНИИОИЗ Минздрава России; 2019.Socially significant diseases of the population of Russia in 2018 (Statistical materials). Alexandrova G.A., Golubev N.A., Tyurina E.M. et al., eds. Russian research Institute of Health; 2019 (in Russ.).
3. Социально значимые заболевания населения России в 2021 году (статистические материалы). Под ред. Стародубова В.И., Александровой Г.А., Голубева Н.А. и др. ЦНИИОИЗ Минздрава России; 2022. DOI: 10.21045/978-5-94116-092-1Socially significant diseases of the population of Russia in 2021 (Statistical materials). Starodubov V.I., Alexandrova G.A., Golubev N.A. et al., eds. Russian research Institute of Health; 2022 (in Russ.). DOI: 10.21045/978-5-94116-092-1
4. Выдров А.С., Комаровских Е.Н. Анализ структуры и динамики офтальмотравматизма в Амурской области. Российский офтальмологический журнал. 2014;1:10–13.Vydrov A.S., Komarovskikh E.N. The structure and dynamics of ocular trauma in the Amur region. Russian Ophthalmological Journal. 2014;1:10–13 (in Russ.).
5. Кузнецов С.Л., Шалдыбина О.В., Галеев Р.С. и др. Эпидемиология обращаемости больных с травмами и острыми заболеваниями глаз и придаточного аппарата по данным кабинета неотложной офтальмологической помощи ГУБЗ «Пензенская областная офтальмологическая больница». Вестник Тамбовского университета. Серия: Естественные и технические науки. 2016;21(4):1597–1606. DOI: 10.20310/1810-0198-2016-21-4-1597-1606Kuznetsov S.L., Shaldybina O.V., Galeev R.S. et al. Epidemiology Of Visits Of Patients With Acute Injuries and Eye Diseases According To Data Of Emergency Eye Care Center of Penza Regional Eye Hospital. Tambov University Review. Natural and Technical Science Series. 2016;21(4):1597–1606 (in Russ.). DOI: 10.20310/1810-0198-2016-21-4-1597-1606
6. Сахарова С.В., Климина Л.В., Бесфатер А.Д. Эпидемиологические особенности глазного травматизма среди госпитальной травмы в Тюменской области за десять лет. Университетская медицина Урала. 2018;3(14):33–35.Sakharova S.V., Klimina L.V., Besfater A.D. Epidemiological features of eye trauma among hospital trauma in the Tyumen region over ten years. University Medicine of the Urals. 2018;3(14):33–35 (in Russ.).
7. Степанянц А.Б., Бобыкин Е.В, Колесникова Е.И. Открытая травма глазного яблока: структура, особенности диагностики и лечения. Уральский медицинский журнал. 2009;1(55):80–83.Stepanyants A.B., Bobykin E.V., Kolesnikova E.I. Open globe injury: structure, features of diagnosis and treatment. Ural Medical Journal. 2009;1(55):80–83 (in Russ.).
8. Yan H. Mechanical Ocular Trauma: Current Consensus and Controversy. 1st ed. Singapore: Springer; 2017. DOI: 10.1007/978-981-10-2150-3
9. Назарян М.Г. Комплексное исследование инвалидности вследствие болезней глаза и его придаточного аппарата и совершенствование системы мер по медико-социальной реабилитации: дис. … д-ра мед. наук. М.; 2019.Nazaryan M.G. Comprehensive study of disability due to diseases of the eye and its adnexa and improvement of the system of measures for medical and social rehabilitation: thesis. M.; 2019 (in Russ.).
10. Арсютов Д.Г., Николаева Т.Ю., Васильева И.В. и др. Витреоретинальная хирургия проникающих ранений с внутриглазным инородным телом. Здравоохранение Чувашии. 2018;3:4–15. DOI: 10.25589/GIDUV.2018.56.16626Arsyutov D.G., Nikolaeva T.Y., Vasilyeva I.V. et al. Vitreoretinal Surgery of Penetrating Wounds with an Intraocular Foreign Body. Health Care of Chuvashia. 2018;3:4–15 (in Russ.). DOI: 10.25589/GIDUV.2018.56.16626
11. Sychev Y.V., Verner-Cole E.A., Suhler E.B. et al. Occult nonmetallic intraocular foreign bodies presenting as fulminant uveitis: a case series and review of the literature. Clin Ophthalmol. 2013;7:1747–1751. DOI: 10.2147/OPTH.S47339
12. Кислицына Н.М., Петраш В.А., Султанова Д.М. и др. Роль компьютерной томографии в тактике офтальмохирурга при осколочных ранениях глазного яблока. Клинический случай. Офтальмология. 2024;21(2):360–364. DOI: 10.18008/1816509520242360364Kislitsina N.M., Petrash V.A., Sultanova D.M. et al. The Role of Computed Tomography in Ophthalmic Surgeon Tactics in Shrapnel Wounds to the Eyeball. Clinical Case. Ophthalmology in Russia. 2024;21(2):360–364 (in Russ.). DOI: 10.18008/1816509520242360364
13. Loporchio D., Mukkamala L., Gorukanti K. et al. Intraocular foreign bodies: A review. Surv Ophthalmol. 2016;61(5):582–596. DOI: 10.1016/j.survophthal.2016.03.005
14. Chiquet C., Zech J.C., Denis P. et al. Intraocular foreign bodies. Factors influencing final visual outcome. Acta Ophthalmol Scand. 1999;77(3):321–325. DOI: 10.1034/j.1600-0420.1999.770315.x
15. Liu X., Bai Q., Song X. Clinical and imaging characteristics, outcomes and prognostic factors of intraocular foreign bodies extracted by vitrectomy. Sci Rep. 2023;13(1):14136. DOI: 10.1038/s41598-023-41105-5
16. Punnonen E., Laatikainen L. Prognosis of perforating eye injuries with intraocular foreign bodies. Acta Ophthalmol (Copenh). 1989;67(5):483–491. DOI: 10.1111/j.1755-3768.1989.tb04097.x
17. Woodcock M.G., Scott R.A., Huntbach J., Kirkby G.R. Mass and shape as factors in intraocular foreign body injuries. Ophthalmology. 2006;113(12):2262–2269. DOI: 10.1016/j.ophtha.2006.06.002
18. Boncoeur-Martel M.P., Adenis J.P., Rulfi J.Y. et al. CT appearances of chronically retained wooden intraorbital foreign bodies. Neuroradiology. 2001;43(2):165–168. DOI: 10.1007/s002340000458
19. You Y., Wang X., Cheng S. et al. Clinical analysis of 96 patients with intraorbital foreign bodies: A 10-year retrospective study. Front Med (Lausanne). 2022;9:1018905. DOI: 10.3389/fmed.2022.1018905
20. Михин А.А., Чурашов С.В., Куликов А.Н., Николаев С.Н. Современная боевая травма глаза. Структура, особенности и исходы лечения. Вестник Национального медико-хирургического центра им. Н.И. Пирогова. 2021;16(1):132–134. DOI: 10.25881/BPNMSC.2021.61.84.025Mihin A.A., Churashov S.V., Kulikov A.N., Nikolaev S.N. Modern combat eye injury. Structure, features and outcomes of treatment. Bulletin of Pirogov National Medical & Surgical Center. 2021;16(1):132–134 (in Russ.). DOI: 10.25881/BPNMSC.2021.61.84.025
21. Blanch R.J., Scott R.A. Military ocular injury: presentation, assessment and management. J R Army Med Corps. 2009;155(4):279–284. DOI: 10.1136/jramc-155-04-08
22. Офтальмология. Национальное руководство. Под ред. Аветисова С.Э., Егорова Е.А., Нероева В.В. и др. М.: ГЭОТАР-Медиа; 2018.Ophthalmology. National Guidelines. Avetisov S.E., Egorov E.A., Neroev V.V. et al., eds. M.: GEOTAR-Media; 2018 (in Russ.).
23. Mester V., Kuhn F. Intraocular foreign bodies. Ophthalmol Clin North Am. 2002;15(2):235–242. DOI: 10.1016/s0896-1549(02)00013-5
24. Atlas of Orbital Imaging. Simon G.B., Greenberg G., Prat D.L., eds. Springer Nature; 2021. DOI: 10.1007/978-3-030-62426-2
25. Bolliger S.A., Oesterhelweg L., Spendlove D. et al. Is differentiation of frequently encountered foreign bodies in corpses possible by Hounsfield density measurement? J Forensic Sci. 2009;54(5):1119–1122. DOI: 10.1111/j.1556-4029.2009.01100.x
26. Momoniat H.T., England A. An investigation into the accuracy of orbital X-rays, when using CR, in detecting ferromagnetic intraocular foreign bodies. Radiography (Lond). 2017;23(1):55–59. DOI: 10.1016/j.radi.2016.09.006
27. Bryden F.M., Pyott A.A., Bailey M., McGhee C.N. Real time ultrasound in the assessment of intraocular foreign bodies. Eye (Lond). 1990;4(Pt5):727–731. DOI: 10.1038/eye.1990.103
28. Chacko J.G., Figueroa R.E., Johnson M.H. et al. Detection and localization of steel intraocular foreign bodies using computed tomography. A comparison of helical and conventional axial scanning. Ophthalmology. 1997;104(2):319–323. DOI: 10.1016/s0161-6420(97)30317-0
29. Rong A.J., Fan K.C., Golshani B. et al. Multimodal imaging features of intraocular foreign bodies. Semin Ophthalmol. 2019;34(7–8):518–532. DOI: 10.1080/08820538.2019.1674894
30. Aras M.H., Miloglu O., Barutcugil C. et al. Comparison of the sensitivity for detecting foreign bodies among conventional plain radiography, computed tomography and ultrasonography. Dentomaxillofac Radiol. 2010;39(2):72–78. DOI: 10.1259/dmfr/68589458
31. Moisseiev E., Last D., Goez D. et al. Magnetic resonance imaging and computed tomography for the detection and characterization of nonmetallic intraocular foreign bodies. Retina. 2015;35(1):82–94. DOI: 10.1097/IAE.0000000000000266
32. McGuckin J.F. Jr, Akhtar N., Ho V.T. et al. CT and MR evaluation of a wooden foreign body in an in vitro model of the orbit. AJNR Am J Neuroradiol. 1996;17(1):129–133. PMID: 8770263
33. Марусина М.Я., Казначеева А.О. Современные виды томографии. Учебное пособие. СПб.: СПбГУ ИТМО; 2006.Marusina M.Ya., Kaznacheeva A.O. Modern types of tomography. Study guide. St. Peterburg: ITMO, 2006 (in Russ.).
34. Javadrashid R., Golamian M., Shahrzad M. et al. Visibility of Different Intraorbital Foreign Bodies Using Plain Radiography, Computed Tomography, Magnetic Resonance Imaging, and Cone-Beam Computed Tomography: аn in vitro Study. Can Assoc Radiol J. 2017;68(2):194–201. DOI: 10.1016/j.carj.2015.09.011
35. Lagalla R., Manfrè L., Caronia A. et al. Plain film, CT and MRI sensibility in the evaluation of intraorbital foreign bodies in an in vitro model of the orbit and in pig eyes. Eur Radiol. 2000;10(8):1338–1341. DOI: 10.1007/s003309900306
36. Gor D.M., Kirsch C.F., Leen J. et al. Radiologic differentiation of intraocular glass: evaluation of imaging techniques, glass types, size, and effect of intraocular hemorrhage. AJR Am J Roentgenol. 2001;177(5):1199–1203. DOI: 10.2214/ajr.177.5.1771199
37. Silverman R.H. Principles of Ophthalmic Ultrasound. Expert Rev Ophthalmol. 2023;18(6):379–389. DOI: 10.1080/17469899.2023.2277781
38. Modjtahedi B.S., Rong A., Bobinski M. et al. Imaging characteristics of intraocular foreign bodies: a comparative study of plain film X-ray, computed tomography, ultrasound, and magnetic resonance imaging. Retina. 2015;35(1):95–104. DOI: 10.1097/IAE.0000000000000271
39. Bhende M., Kamat H., Krishna T. et al. The Sankara Nethralaya Atlas of Ophthalmic Ultrasound and Ultrasound Biomicroscopy. 2nd ed. New Delhi: Jaypee Brothers; 2013.

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