Clinical and neurospychological patterns of ongoing symptomatic COVID-19 and postcovid syndrome
Yu.V. Evsyutina^1, A.B. Danilov^1,2, E.G. Filatova¹, A.V. Simonova<sup>3

1</sup>I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow
²Institute of Interdisciplinary Medicine, Moscow
³M.F. Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow

Background: nowadays, there is a relevance about the assessing the long-term consequences of SARS-CoV-2 due to the growth of the patient population recovering from COVID-19, as well as a decrease in the life quality of this patient cohort. According to the existing classification and depending on the symptom duration, patients with long-term effects of coronavirus infection can be divided into ongoing symptomatic COVID-19 and postcovid syndrome.
Aim: to determine the clinical and neurospychological patterns of the ongoing symptomatic COVID-19 and postcovid syndrome in indoor patients after the identified new coronavirus infection SARS-CoV-2.
Materials and Methods: 60 male and female patients aged 19 to 71 years were comprehensively examined. These patients were divided into two groups: group 1 included patients with ongoing symptomatic COVID-19, while group 2 included patients with postcovid syndrome.
Results: during the data analysis, it was revealed that the mean period of seeking medical help from the disease onset in patients with ongoing symptomatic COVID-19 was 6.12 weeks, and in patients with postcovid syndrome — 16.07 weeks. The patients of both groups did not differ in the disease severity and the affected lung tissue volume, as well as laboratory parameters, and also had similar chronic diseases. One of the most common clinical manifestations in both groups is fatigue and general weakness: 87.9% in group 1 and 77.8% in group 2. In both groups, there was an olfactory disorder in the form of hyposmia. The average total score of MFI-20 indicates the presence of asthenic syndrome in both groups. In general, the asthenia patterns in patients of both groups were similar. It was also found that the anxiety level in group 1 corresponded to a high value, and in group 2 — to a very high. The MoCA average score indicated the presence of moderate cognitive impairment.
Conclusion: the study results did not show statistical differences in clinical, neuropsychological and laboratory characteristics between patients with ongoing symptomatic COVID-19 and postcovid syndrome.
Keywords: ongoing symptomatic COVID-19, postcovid syndrome, neuropsychic manifestations, asthenia, cognitive impairment, anxiety, depression, stress, hyposmia.
For citation: Evsyutina Yu.V., Danilov A.B., Filatova E.G., Simonova A.V. Clinical and neurospychological patterns of ongoing symptomatic COVID-19 and postcovid syndrome. RMJ. 2024;4:30–35.