Arterial hypertension in the very elderly patients: the significance of senile asthenia
Kotovskaya Yu.V.^1,2, Tkacheva О.N.¹, Runikhina N.K.¹, Ostapenko V.S.¹, Luzina A.V.<sup>1

1</sup> Russian gerontological scientific and clinical center, Moscow
² Peoples' Friendship University of Russia, Moscow

Planning of  the therapeutic interventions in the elderly patients is impossible without taking into account the influence of the therapy on physical and cognitive functioning. Despite the convincing evidence of an unfavorable predictive value of high blood pressure (BP) in middle-aged people, its effect on prognosis in the very elderly people is still discussed, as well as the question of whether to treat arterial hypertension (AH) in elderly patients, and how intensively. The review presents data of observational and randomized clinical trials that allow us to say that it is not the chronological but the biological age (senile asthenia), that becomes an important criterion for choosing the treatment of  hypertension in the elderly patients. The article discusses in detail the mechanisms involved in the regulation of blood pressure, as well as the influence of BP on the risk of morbidity and mortality in patients of senile age. Recommendations for antihypertensive therapy in elderly and senile patients are given.

Key words: arterial hypertension, orthostatic hypotension, very elderly people, senile asthenia, biological age.
For citation: Kotovskaya Yu.V., Tkacheva О.N., Runikhina N.K. et al. Arterial hypertension in the very elderly patients: the significance of senile asthenia // RMJ.  2017. № 25. P. 1829–1832.