Clinical case of secondary syphilis in an HIV-infected patient
DOI: 10.32364/2587-6821-2021-5-11-778-781
S.V. Koshkin1, A.L. Evseev1, V.V. Ryabova1, O.S. Kovrova2
1Kirov State Medical University, Kirov, Russian Federation
2Kirov Regional Clinical Dermatovenerologic Dispensary, Kirov, Russian Federation
Syphilis is one of the urgent problems in modern dermatovenerology. Despite the comprehensive study and wide popularity of the disease, certain diagnostic difficulties arise in some clinical situations. In recent years, there has been a downward trend in the syphilis incidence in the Russian Federation, while the number of HIV-infected people is steadily increasing. The presence of both infections in the patient simultaneously aggravates the clinical picture, and is commonly the cause of diagnostic errors, contributing to the disease spread among the population. The article presents a clinical case of a young female patient with secondary syphilis associated with HIV infection, hepatitis C, gonorrhea and trichomoniasis. Secondary syphilis was detected randomly, in an AIDS center. Despite repeated hospitalizations, it was not possible to conduct complete treatment of syphilis due to the patient’s unwillingness to be treated and her unauthorized leaving of the healthcare facility. In this publication, we would like to draw attention to the disease as a problem of modern society: a conniving attitude and lack of responsibility contribute to the spread of syphilitic infection.
Keywords: secondary syphilis, HIV infection, mixed infection, sexually transmitted infections, benzylpenicillin.
For citation: Koshkin S.V., Evseev A.L., Ryabova V.V., Kovrova O.S. Clinical case of secondary syphilis in an HIV-infected patient. Russian Medical Inquiry. 2021;5(11):778–781 (in Russ.). DOI: 10.32364/2587-6821-2021-5-11-778-781.
About the authors:
Sergey V. Koshkin — Dr. Sc. (Med.), Professor, Head of the Department of Dermatovenerology and Cosmetology, Kirov State Medical University; 112, Karl Marks str., Kirov, 610027, Russian Federation.
Anna L. Evseeva — Senior Professor of the Department of Dermatovenerology and Cosmetology, Kirov State Medical University; 112, Karl Marks str., Kirov, 610027, Russian Federation.
Vera V. Ryabova — Assistant Professor of the Department of Dermatovenerology and Cosmetology, Kirov State Medical University; 112, Karl Marks str., Kirov, 610027, Russian Federation.
Olga S. Kovrova — Head of the Department of Venerology, Kirov Regional Clinical Dermatovenerologic Dispensary; 2A, Semashko str., Kirov, 610030, Russian Federation.
Contact information: e-mail: koshkin_sergei@mail.ru,
Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.
There is no conflict of interests.
Received 15.01.2021.
Revised 09.02.2021.
Accepted 09.03.2021.
2. Koshkin S.V., Chermnykh T.V. Clinical manifestations of early forms of syphilis. Atlas. Visual Aids for Doctors. Kirov: Kirov SMA; 2011 (in Russ.).
3. Potekaev N.N., Frigo N.V., Almazova A.A. et al. Epidemiology of syphilis in modern conditions. Clinicheskaya dermatologiya i venerologiya. 2015;14(1): 22–34 (in Russ.). DOI: 10.17116/klinderma2015122-34.
4. Astvacaturov K.R. Syphilis, diagnosis and therapy. M.: Medgis; 1971 (in Russ.).
5. Krasnoselskikh T.V., Sokolovskiy E.V. Neurosyphilis in HIV-infected patients. Vestnik Dermatologii i Venerologii. 2015;(2): 49–57 (in Russ.).
6. Pirogova I.A. The prevalence of HIV infection in Russia. Bulletin of the Council of young scientists and specialists of Chelyabinsk region. 2017;4(19):45–49 (in Russ.).
7. Buchacz K., Patel P., Taylor M. et al. Syphilis increases HIV viral load and decreases CD4 cell counts in HIV-infected patients with new syphilis infections. AIDS. 2004;18(15):2075–2079.
8. Butov Yu.S., Potekaev N.N. Dermatovenereology: a guide for doctors. M.: GEOTAR-Media; 2017 (in Russ.).
9. Koshkin S.V., Chermnykh T.V., Zaitseva G.А. et al. Associative connection of secondary syphilis of skin and mucous membranes with the histocompatibility antigenes of the first class. Vestnik dermatologii i venerologii. 2017; 2:27–33 (in Russ.).
10. Clinical guidelines "Syphilis". 2020 (Electronic resource.) URL: http://cr.rosminzdrav.ru/#!/recomend/836.
11. Glebova L.I., Stoyanova G.N., Kuleshov A.N. et al. Extraginethal localization of hard chancre in syphilis in practice of a doctor-stomatologist. Stomatolog-praktik. 2014;3:72–73 (in Russ.).
12. Shmagel K.V., Chereshnev V.A. Immune status in HIV-infected patients coinfected with hepаtitis C virus (HCV). HIV Infection and Immunosuppressive Disorders. 2018;10(4):25–36 (in Russ.). DOI: 10.22328/2077-9828-2018-10-4-25-36.
13. Krasnoselskikh T.V., Shaboltas A.V. Multidisciplinary approach to the prevention of sexually transmitted infections and blood-borne infections. HIV Infection and Immunosuppressive Disorders. 2018;10(4):100–112 (in Russ.). DOI: 10.22328/2077-9828-2018-10-4-100-112.
14. Salamov G.G., Detkova N.V. HIV infection, viral hepatitis and syphilis in persons engaged in prostitution. J. Epidemiology and infectious diseases. 2001;1:20–22 (in Russ.).
This work is licensed under a Creative Commons «Attribution» 4.0 License.
