Comparative outcomes of treatment of polycystic ovarian syndrome using optimized surgical techniques
DOI: 10.32364/2618-8430-2024-7-3-4
Yu.E. Dobrokhotova, I.I. Grishin, I.Yu. Il'ina, O.R. Ogede
Pirogov Russian National Research Medical University, Moscow, Russian Federation
Aim: to optimize the algorithm for surgical management of polycystic ovary syndrome (PCOS) in women with impaired reproductive function and infertility.
Patients and Methods: the study included 60 women of reproductive age between 18 and 35 years with PCOS and infertility. Group 1 consisted of 30 women (mean age 26.9±4.8 years) who underwent energy-free laparoscopic ovarian drilling (during the procedure, the tunica albuginea was destroyed with endoscopic scissors). Group 2 consisted of 30 women who underwent CO2 laser drilling. There were no significant differences between the groups in menstrual function, number of pregnancies, gynecological and extragenital diseases. The treatment effect on ovulation, menstrual cycle, fertility, pregnancy, and hormone levels was evaluated 1 month and 3 months after surgery.
Results: аfter surgery, a significant decrease in the number of complaints, including menstrual disturbances, was reported in all women in groups 1 and 2. A significant decrease in the levels of luteinizing hormone (LH), anti-Müllerian hormone, and free testosterone, as well as in the ratio of LH to follicle-stimulating hormone (FSH), was observed in both groups. The groups differed significantly (p <0.05) in ovulation and pregnancy rates. Ovulation occurred in 28 (93.33%) women in group 1 and 21 (70%) women in group 2. Pregnancy occurred in 26 (86.66%) and 18 (60%) women, respectively. There were no postoperative complications in either group.
Conclusions: energy-free laparoscopic ovarian drilling for PCOS resulted in a higher rate of spontaneous pregnancy compared to laser drilling.
Keywords: infertility, laparoscopic ovarian drilling, polycystic ovary syndrome, energy-free laparoscopic ovarian drilling, laser drilling.
For citation: Dobrokhotova Yu.E., Grishin I.I., Il'ina I.Yu., Ogede O.R. Comparative outcomes of treatment of polycystic ovarian syndrome using optimized surgical techniques. Russian Journal of Woman and Child Health. 2024;7(3):222–226 (in Russ.). DOI: 10.32364/2618-8430-2024-7-3-4.
About the authors:
Yulia E. Dobrokhotova — Dr. Sc. (Med.), Professor, Head of the Department of Obstetrics and Gynecology of the Medical Faculty, Pirogov Russian National Research Medical University; 1, Ostrovityanov str., Moscow, 117997, Russian Federation; ORCID iD 0000-0002-7830-2290.
Igor I. Grishin — Dr. Sc. (Med.), Professor of the Department of Obstetrics and Gynecology of the Medical Faculty, Pirogov Russian National Research Medical University; 1, Ostrovityanov str., Moscow, 117997, Russian Federation; ORCID iD 0000-0001-5839-1858.
Irina Yu. Ilyina — Dr. Sc. (Med.), Professor of the Department of Obstetrics and Gynecology of the Medical Faculty, Pirogov Russian National Research Medical University; 1, Ostrovityanov str., Moscow, 117997, Russian Federation; ORCID iD 0000-0001-8155-8775.
Olade R. Ogede — postgraduate student of the Department of Obstetrics and Gynecology of the Medical Faculty, Pirogov Russian National Research Medical University; 1, Ostrovityanov str., Moscow, 117997, Russian Federation; ORCID iD 0000-0003-1433-8144.
Contact information: Yulia E. Dobrokhotova, e-mail: pr.dobrohotova@mail.ru.
Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.
There is no conflict of interest.
Received 10.06.2024.
Revised 04.07.2024.
Accepted 29.07.2024.
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