Realization of fertility after cervical ectopic pregnancy: a case study
DOI: 10.32364/2618-8430-2025-8-1-6
E.V. Vartanyan1,2, P.A. Kiryushenkov2.3, A.V. Kozachenko4, E.A. Devyatova2, K.A. Tsaturova1,2
1Pirogov Russian National Research Medical University, Moscow, Russian Federation
2IVF Clinic "DIP", Moscow, Russian Federation
3RUDN University, Moscow, Russian Federation
4V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology,
Moscow, Russian Federation
The modern approach to managing cervical pregnancy (CP) prioritizes the implementation of an optimized algorithm for diagnosis and treatment, integrating advanced high-tech techniques at all stages of care. This article reports a clinical case involving a 31-year-old female patient diagnosed with CP. Following comprehensive, high-tech therapeutic interventions, the patient successfully achieved restoration of her reproductive function. Diagnostic methodologies employed included the measurement of the β-subunit of human chorionic gonadotropin levels in blood serum, pelvic ultrasonography, and magnetic resonance imaging for detailed visualization of the gestational sac and assessment of the interface between the chorion and the cervical stroma. Standard general clinical tests were also conducted to support the diagnostic process. The treatment tactics comprised low-dose metronomic chemotherapy, selective uterine artery embolization, and subsequent curettage of the cervical canal and uterine cavity under hysteroscopic guidance. This organ-sparing, multimodal therapeutic approach was instrumental in minimizing the risk of hemorrhage and preserving the patient's reproductive potential for the delayed period.
Keywords: cervical pregnancy, ectopic pregnancy, uterine artery embolization, fertility preservation, miscarriage.
For citation: Vartanyan E.V., Kiryushenkov P.A., Kozachenko A.V., Devyatova E.A., Tsaturova K.A. Realization of fertility after cervical ectopic pregnancy: a case study. Russian Journal of Woman and Child Health. 2025;8(1):38–42 (in Russ.). DOI: 10.32364/2618-8430-2025-8-1-6
ABOUT THE AUTHORS:
Emma V. Vartanyan — Dr. Sc. (Med.), Associate Professor, Professor of the Department of Obstetrics and Gynecology, Pirogov Russian National Research Medical University; 1, Ostovityanov str., Moscow, 117513, Russian Federation; IVF Clinic "DIP"; 2, Schukinskaya str., Moscow, 123182, Russian Federation; President of the Self-Regulatory Society "Association of ART Clinics"; ORCID iD 0000-0003-0337-086X
Peter A. Kiryushenkov — Dr. Sc. (Med.), Head of the Clinical Hemostasiology Course at the Faculty of Advanced Training of Medical Specialists; RUDN University; 6, Miklukho-Maklaya str., Moscow, 117198, Russian Federation; obstetrician-gynecologist, IVF Clinic "DIP"; 2, Schukinskaya str., Moscow, 123182, Russian Federation; ORCID iD 0009-0008-1459-8038
Andrey V. Kozachenko — Dr. Sc. (Med.), Leading Researcher at the V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology and Perinatology; 4, Academician Oparin str., Moscow, 117997, Russian Federation; ORCID iD 0000-0001-5343-250X
Ekaterina A. Devyatova — C. Sc. (Med.), Deputy Chief Medical Officer, ultrasound physician, obstetrician-gynecologist, IVF Clinic "DIP"; 2, Schukinskaya str., Moscow, 123182, Russian Federation; ORCID iD 0000-0003-1533-1593
Kristina A. Tsaturova — C. Sc. (Med.), Assistant Professor at the Department of Obstetrics and Gynecology, Pirogov Russian National Research Medical University; 1, Ostovityanov str., Moscow, 117513, Russian Federation; IVF Clinic "DIP"; 2, Schukinskaya str., Moscow, 123182, Russian Federation; Chief Medical Officer, obstetrician-gynecologist, fertility specialist, IVF Clinic "DIP"; 2, Schukinskaya str., Moscow, 123182, Russian Federation; ORCID iD 0000-0002-1095-4700
Contact information: Ekaterina A. Devyatova, e-mail: devyatova@baby-ivf.ru
Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.
There is no conflict of interest.
Received 25.01.2024.
Revised 19.02.2024.
Accepted 18.03.2024.
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