Histological aspects of endometritis
DOI: 10.32364/2618-8430-2026-9-3-11
Histological aspects of endometritis
S.B. Nemanova1,2, A.N. Baranov1, S.A. Nemanova1, K.O. Bokareva1
1 Northern State Medical University, Arkhangelsk, Russian Federation
2 Severodvinsk City Clinical Hospital of the Emergency Medical Care No. 2, Severodvinsk, Russian Federation
The review highlights histological characteristics of acute and chronic endometritis. Аim: to analyse scientific literature data describing histological manifestations of endometritis. A total of 245 sources were analysed. Open access papers from Google Scholar, PubMed, eLIBRARY, and CyberLeninka (search period: 2017-2025) were used for the study. Full-text articles, literature reviews, and original researches were selected for the analysis.
The review included data reporting histological features of acute (AE) and chronic endometritis (CE) considering etiology, morphotype, and CE course variant. Attention is paid to complicated pathomorphological identification of CE associated with high variability of morphological presentation in the endometrium. Also, the review is focused on differential diagnosis of specific and nonspecific chronic endometritis.
Although histological examination (HE) is a highly effective method to diagnose endometritis, it may demonstrate false results such as hypodiagnosis in case of incomplete morphological picture of chronic endometritis, and hyperdiagnosis in some cases of acute and chronic endometritis when subjective assessment of histological glandular-stromal endometrial characteristics is performed.
As a primary available method to diagnose endometrial condition, HE cannot always verify CE. Therefore, additional advanced methods of morphological diagnosis should be applied. However, routine HE remains an actual main method to assess endometrial compliance with a day of a menstrual cycle relative to a biopsy day, secretory transformation adequacy and presence of an inflammatory vascular component, as well as fibroplastic changes in the endometrium.
Keywords: endometritis, chronic endometritis, inflammatory endometrial disorder, endometritis pathomorphology, morphological diagnosis, endometritis diagnosis, histological examination, endometrial fibrosis.
For citation: Nemanova S.B., Baranov A.N., Nemanova S.A., Bokareva K.O. Histological aspects of endometritis. Russian Journal of Woman and Child Health. 2026;9(3):297–303 (in Russ.). DOI: 10.32364/2618-8430-2026-9-3-11
About the authors:
Svetlana B. Nemanova — C. Sc. (Med.), Teaching Assistant, Department of Obstetrics and Gynecology, Northern State Medical University; 51, Troitskiy ave., Arkhangelsk, 163000, Russian Federation; Obstetrician-Gynecologist, Pathologist, Pathology Department, Severodvinsk City Clinical Hospital of the Emergency Medical Care No. 2; 49, Morskoy ave., Severodvinsk, 164500, Russian Federation; ORCID iD 0000-0001-7459-4057
Alexey N. Baranov — Dr. Sc. (Med.), Professor, Head of the Department of Obstetrics and Gynecology, Northern State Medical University; 51, Troitskiy ave., Arkhangelsk, 163000, Russian Federation; ORCID iD 0000-0003-2530-0379
Sofia A. Nemanova — Clinical Resident at the Department of Obstetrics and Gynecology, Northern State Medical University; 51, Troitskiy ave., Arkhangelsk, 163000, Russian Federation; ORCID iD 0009-0003-8626-556X
Karina O. Bokareva — Clinical resident at the Department of Obstetrics and Gynecology, Northern State Medical University; 51, Troitskiy ave., Arkhangelsk, 163000, Russian Federation; ORCID iD 0009-0001-6924-3233
Contact information: Alexey N. Baranov, e-mail: a.n.baranov2011@yandex.ru
Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.
There is no conflict of interest.
Received 13.12.2025.
Revised 15.01.2026.
Accepted 09.02.2026.
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