Modern view on the possibility of intestinal microbiocenosis correction
Gasilina T.V., Belmer S.V.

Russian National Research Medical University named after N.I. Pirogov

Over the past decade our knowledge of the human intestinal microbiocenosis has significantly expanded and deepened. Currently, more than 70,000 species of microorganisms inhabiting the large intestine and performing vital functions are known. The important role of intestinal microbes in the development of many diseases, including irritable bowel syndrome, inflammatory bowel disease, obesity, type II diabetes, atherosclerosis, autism and multiple sclerosis has been established. In this regard, prevention of dysbiosis and its correction seem to be important tasks in the treatment of these diseases, which are solved not only by prescribing pre- and probiotics. Dysbiosis is always a secondary disorder, so finding a significant state in its development or disease with subsequent correction is an important task. Correction of dysbiotic disorders should begin with the elimination of the cause.
Pro- and prebiotics are prescribed in combination with antibacterial drugs. One of these drugs is nifuratel, which has shown its effectiveness and safety both in children and adults in numerous domestic and foreign studies. An important feature of nifuratel is that it promotes an increase in the number of bifidobacteria and lactobacilli, having a broad spectrum of action, suppressing the growth of opportunistic microflora of the intestine.

Key words: intestinal microflora, dysbiosis, small bowel bacterial overgrowth syndrome (SBBOS), prebiotics, probiotics, nifuratel.
For citation: Gasilina T.V., Belmer S.V. Modern view on the possibility of intestinal microbiocenosis correction // RMJ. 2017. № 10. P.726 –729.