A patient with functional biliary disorder. Specificity of therapeutic management

I.G. Pakhomova

V.A. Almazov National Medical Research Center, St. Petersburg

In recent years, the dramatic growth of functional gastrointestinal disorders (including biliary tract disorders) has been reported. Numerous factors (e.g., unhealthy diet, obesity, psychogenic factors, etc.) account for this phenomenon. In addition, diagnostic armamentarium has significantly improved. Functional biliary disorders include gallbladder and sphincter of Oddi dysfunction. This paper describes diagnostic approaches and management in a woman with functional gallbladder disorder. A complex algorithm involving changes in diet, lifestyle, and psychology is of crucial importance. Antispasmodics are among first-line medications. They target cystic duct sphincter in gallbladder dysfunction and sphincter of Oddi in its dysfunction. Therefore, medications with a selective effect on the biliary tract should be prescribed to achieve the maximum effect and minimize adverse reactions of functional biliary disorder treatment. Hymecromone, which provides a selective antispasmodic effect on the sphincter of Oddi and cystic duct, is considered one of these agents.

Keywords: functional biliary disorder, gallbladder dyskinesia, biliary pain, antispasmodics, hymecromone.

For citation: Pakhomova I.G. A patient with functional biliary disorder. Specificity of therapeutic management. RMJ. 2022;3:13–19.