Clinical case of sebaceous gland ectopia in the esophagus — characteristics of endoscopic diagnosis
DOI: 10.32364/2587-6821-2023-7-5-10
V.V. Lozovaya1, O.A. Gusarova1, O.A. Malikhova1,2, A.O. Tumanyan1
1N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russian Federation
2Russian Medical Academy of Continuous Professional Education, Moscow, Russian Federation
In most of the previously discussed cases, sebaceous gland ectopia (SGE) was described in tissues derived from the ectoderm. Only a small number of publications reported cases of SGE in the esophagus (endoderm organ). The article presents a clinical case of a 68-year-old male patient without complaints from the gastrointestinal tract, however, there were multiple white overlays in the distal esophagus revealed during esophagogastroduodenoscopy. After the morphological examination, the diagnosis of SGE of the esophagus was established. Currently, there is no data in the world literature on the possible malignant transformation of SGE in the esophagus. In an asymptomatic disease course, this group of patients does not need specific drug therapy and/or endoscopic mucosal resection. If there are symptoms of reflux esophagitis, anti-reflux therapy may be prescribed. The main and, most likely, the only possible method of diagnosing this form of neoplasia is endoscopic, accompanied by the mandatory sampling of biopsy material for morphological examination. Conducting a standard EGDS must necessarily include examination using narrow-band imaging or chromoendoscopy of the esophageal mucosa.
Keywords: sebaceous gland ectopia, endoscopy, esophagus, narrow-band imaging, esophagogastroduodenoscopy, chromoendoscopy.
For citation: Lozovaya V.V., Gusarova O.A., Malikhova O.A., Tumanyan A.O. Clinical case of sebaceous gland ectopia in the esophagus — characteristics of endoscopic diagnosis. Russian Medical Inquiry. 2023;7(5):318–322 (in Russ.). DOI: 10.32364/2587-6821-2023-7-5-10.
About the authors:
Valerya V. Lozovaya — endoscopist of the Endoscopic Department of the N.N. Trapeznikov Research Institute of Clinical Oncology, N.N. Blokhin National Medical Research Center of Oncology; 23, Kashirskoe highway, Moscow, 115478, Russian Federation; ORCID iD 0000-0001-6262-7763.
Olga A. Gusarova — resident and endoscopist of the Endoscopic Department of the N.N. Trapeznikov Research Institute of Clinical Oncology, N.N. Blokhin National Medical Research Center of Oncology; 23, Kashirskoe highway, Moscow, 115478, Russian Federation; ORCID iD 0000-0001-6179-1115.
Olga A. Malikhova — Dr. Sc. (Med.), endoscopist, Head of the Endoscopic Department of the N.N. Trapeznikov Research Institute of Clinical Oncology, N.N. Blokhin National Medical Research Center of Oncology; 23, Kashirskoe highway, Moscow, 115478, Russian Federation; Professor of the Department of Oncology and Palliative Care, Russian Medical Academy of Continuous Professional Education; 2/1, bldn. 1, Barrikadnaya str., Moscow, 125993, Russian Federation; ORCID iD 0000-0003-0829-7809.
Armen O. Tumanyan — Dr. Sc. (Med.), endoscopist, Senior Researcher of the Scientific Advisory Department of the N.N. Trapeznikov Research Institute of Clinical Oncology, N.N. Blokhin National Medical Research Center of Oncology; 23, Kashirskoe highway, Moscow, 115478, Russian Federation; ORCID iD 0000-0001-5863-5197.
Contact information: Olga A. Gusarova, e-mail: o.a.gusarova@mail.ru.
Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.
There is no conflict of interests.
Received 16.10.2022.
Revised 09.11.2022.
Accepted 02.12.2022.
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