Antibiotics as modulators of intestinal microbiota: between the good and the bad
Plotnikova E.Yu., Zakharova Yu.V.

Kemerovo State Medical University

Obesity is progressing in a number of countries around the world with a real epidemic speed. Microbiomas play an important role in maintaining health, immunity and metabolism. Today antibiotics are invaluable drugs used in the treatment of many serious infections and they continue to save countless number of lives. Side effects from antibiotic treatment on the intestinal microflora range from a self-limited «functional» diarrhea to a life-threatening pseudomembranous colitis. New epidemiological studies have shown that the use of antibiotics is associated with an increased risk of overweight and obesity. But it is not only antibiotic therapy that may cause the disturbance of intestinal microflora. Antibiotics are widely used as growth stimulators in agriculture, they are accumulated in the meat of animals and poultry that we eat. Probiotics are agents that can modulate and improve the intestinal microflora during antibiotic therapy. Probiotics not only prevent and treat antibiotic-associated diarrhea, but also contribute to weight loss and reduce overweight, they can improve immunity, prevent colds and atopic diseases, and also have many other effects.

Key words: obesity, antibiotics, antibiotic therapy, probiotics, Maxilac.
For citation: Plotnikova E.Yu., Zakharova Yu.V. Antibiotics as modulators of intestinal microbiota: between the good and the bad // RMJ. 2018. № 11(II). P. 131–136.