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Modern view on treatment of chronic diffuse telogenous alopecia in men

Abstract


O.Yu. Olisova, A.A. Lepyokhova

Sechenov University, Moscow

Androgenetic alopecia (AGA) occurs in 80% of men and 40% of women and is characterized by a gradual thinning of terminal hair, turning them into vellus and further loss. With AGA, there is a progressive shortening of the anagen phase, prolongation of the post-exogenous phase of the telogen (latent phase of the kenogen) and, finally, miniaturization of the hair follicle.
Aim: to study the efficacy of Neoptide Men lotion in hair loss in patients with AGA.
Patients and Methods: there were 30 men aged from 32 to 58 years with a diagnosis of AGA III–V degree on the Hamilton-Norwood scale under our observation. Parietal and occipital areas were photographed with a 200-fold and 60-fold magnification for each patient. The evaluation criteria were: the amount of vellus; thickness of hair — percentage of thin (40–60 microns), medium (60–80 microns) and thick (more than 80 microns); percentage of single, double, triple follicular units, the amount of yellow dots, percentage of perifollicular inflammation. The Neoptide Men lotion were administered once a day for 6 months.
Results: after 6 months of treatment, a decrease in the percentage of fine hair (31% and 25%), an increase in the percentage of medium (39% and 43%) and thick hair (30% and 35%) in the parietal and occipital zones, respectively. The ratio of single follicular units was 1:1, anisotrichosis and the amount of yellow dots in the frontal zone — 9.6% and 1%, respectively. The percentage of perifollicular inflammation was 15%. No side effects (including allergic reactions) were observed with the use of the Neoptide Men lotion.
Conclusion: Neoptide Men lotion for men is an effective and safe treatment for AGA III–IV degree.

Key words: androgenetic alopecia, alopecia, minoxidil, Neoptide Men lotion.
For citation: Olisova O.Yu., Lepyokhova A.A. Modern view on treatment of chronic diffuse telogenous alopecia in men // RMJ. Medical Review. 2018. № 5. P. 47–51.
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