Application of physiotherapeutic methods in the treatment of patients with psoriasis
E.A. Batkaev, I.A. Chistyakova

RUDN University, Moscow

Modern treatment methods of severe forms of psoriasis include so-called genetically engineered biologic drugs containing monoclonal antibodies that neutralize crucial cytokines. Most drugs for biologic therapy have a good therapeutic effect already after 3–6 months from the start of treatment, however, in some patients, an “effect escape” may develop, which is mainly due to the appearance of neutralizing antibodies to monoclonal antibodies contained in these drugs, and leads to the use of cytostatics. The effectiveness of the treatment of psoriasis increases significantly with the co-use of drugs and physiotherapy methods. One of the most active methods is an ultraviolet therapy of various spectral ranges.
Photochemotherapy (PUVA therapy) is one of the most effective modern methods of psoriasis phototherapy. Clinical recovery is achieved in 75–92% of cases. The article presents the successful experience of 5-year-long use of the drug Ammifurin^® in almost twice increased doses (1.5 mg/kg). We believe that the PUVA therapy method should be applied more widely for patients with psoriasis in the conditions of our country, preferring it over corticosteroids, with which relapses are more common.

Key words: physiotherapy, ultraviolet therapy, genetic engineered biologic drugs, cytostatics, psoriasis, photochemotherapy, Ammifurin^®.
For citation: Batkaev E.A., Chistyakova I.A. Application of physiotherapeutic methods in the treatment of patients with psoriasis // RMJ. 2018. № 8(II). P. 102–103.