Pathogenetic aspects concerning the usage of the main methods in aesthetic medicine for involutional skin changes

N.N. Potekaev^1,2, O.B. Borzykh³, E.I. Karpova¹, M.M. Petrova³, N.A. Schneider^3,4, O.M. Demina¹, M.A. Zatolokina⁵ 

¹Pirogov Russian National Research Medical University, Moscow

²Moscow Research and Practical Center for Dermatovenerology and Cosmetology, Moscow

³Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk

⁴V.M. Bekhterev National Medical Research Center for Psychiatry and Neurology, St. Petersburg

⁵Kursk State Medical University, Kursk

With an increase in the total life expectancy, the need for long-term maintenance of the organ physiological functions, including the skin, increases too. The skin is not only a protective barrier for internal organs but also a source of information about a person’s health and age for others. Thus, its social function is manifested. In this regard, it is not surprising that the number of aesthetic procedures aimed at correcting age-related skin changes is steadily growing worldwide. There are more and more new methods that promise grandiose results. Different methods of aesthetic medicine realize their rejuvenating effects through various mechanisms. Only the Global Aesthetic Improvement Scale (GAIS) is not enough for a real evaluation of the procedure efficacy. It is necessary to understand the changes occuring at the tissue, cellular and even molecular l evel. In order to prescribe a comprehensive treatment of involutional skin changes, a cosmetologist and a dermatologist need to understand the pathogenetic aspects of skin aging in combination with those pathogenetic changes that occur during using certain methods of aesthetic correction. The aim of this review was to combine the available information on pathogenetic changes during skin aging with the available information on the effects of the main techniques used in cosmetology. Special attention is paid to histological, cellular and molecular changes in the use of biorevitalization and collagen stimulators.

Keywords: skin aging, aesthetic medicine, rejuvenation, cosmetology, biorevitalization, collagen stimulators, hyaluronic acid, collagen.

For citation: Potekaev N.N., Borzykh O.B., Karpova E.I. et al. Pathogenetic aspects concerning the usage of the main methods in aesthetic medicine for involutional skin changes. RMJ. 2022;8:48–54.