Clinical aspects and diagnostics complications of localized scleroderma rare forms

M.M. Tlish, N.L. Sycheva, A.V. Oblomiy, N.V. Sorokina, F.A. Psavok

Kuban State Medical University, Krasnodar

Localized scleroderma refers to chronic autoimmune dermatoses and is characterized by the local inflammation foci manifestation in various body parts with subsequent skin sclerosis and/or skin atrophy formation and underlying tissues. The article highlights the main etiology, pathogenesis and clinical manifestations aspects of the disease. An in-house follow-up case study of patients with a clinical picture untypical for plaque scleroderma demonstrates the diagnostic process complexity.

The first patient had cutaneous eruptions on her body, which were of an unusual ring-shaped form and resembled the atrophic form of lichen planus or granuloma annulare. Two other patients were diagnosed with deep scleroderma on the lower extremities, which during its onset simulated clinical manifestations of vasculitis, lupus erythematosus or toxicoderma, what brought to delayed diagnosis. In some cases, localized scleroderma requires  a more meticulous patients examination with pathohistological study application, as early diagnostics and timely beginning of treatment can stop disease progression and minimize atrophic and sclerotic process consequences, improving by that patient’s life quality.

Keywords: skin, localized scleroderma, plaque scleroderma, deep scleroderma, diagnosis, pathohistological study.

For citation: Tlish M.M., Sycheva N.L., Oblomiy A.V. et al. Clinical aspects and diagnostics complications of localized scleroderma rare forms. RMJ. 2019;4:62–66.