Hidradenitis suppurativa (acne inversa). Diagnostic criteria, modern therapy

Yu.A. Gallyamova, A.S. Kravchenko

Russian Medical Academy of Continuous Professional Education, Moscow 

The article presents a literature review devoted to a serious disease — hidradenitis suppurativa (acne inversa) (HS/AI), which modern diagnosis, classification and therapy are considered in detail. Despite the long-term study of the problem, there is no integrated approach to the treatment of HS/AI, characterized by a long-lasting torpid course with difficult achievement of remissions. This article is addressed to medical practitioners in order to help in the differential diagnosis and determination of the disease severity. The article also describes the main clinical differential diagnostic criteria of HS/AI, since the diagnosis is still made on the basis of the clinical picture (not the histological), due to the absence of specific changes in the latter. Based on the modern literature data, various treatment approaches concerning the use of various drug groups (antibiotics, retinoids, corticosteroids, cytostatics and biological drugs) are analyzed, depen ding on the severity of HS/AI and the response to treatment. Contradictions in the efficacy evaluation of a number of drugs and insufficient evidence in favor of using different laser types are also noted. The article outlines the main directions of modern research on the disease pathogenesis, which can open up new therapy possibilities.

Keywords: hidradenitis suppurativa, acne inversa, acne conglobate, follicular occlusion syndrome, pilonidal cyst.

For citation: Gallyamova Yu.A., Kravchenko A.S. Hidradenitis suppurativa (acne inversa). Diagnostic criteria, modern therapy. RMJ. 2022;8:43–47.