Features of infants’ skin care in dermatoses
Tamrazova O.B.1, 2, Kasyanova A.N.3, Zaplatnikov A.L.2, 3
1 RUDN University, Moscow
2 Children’s City Clinical Hospital n. a. Bashlyaeva Z. A., Moscow
3 Russian Medical Academy of Сontinuous Professional Education, Moscow
Skin is a unique organ with its physiology and anatomy. At the same time, the skin, as an organ, performs many important functions, including barrier-protective, receptor, thermoregulatory, immune, respiratory, secretory, metabolic, etc. The article describes in detail the main functions of the skin and the anatomical and physiological features of the skin of infants. An extensive review of dermatoses of young children and methods of their treatment are given. Proper infants’ skin care is the basis for the prevention of various infectious and allergic skin lesions of the child, including atopic dermatitis. The use of D-Panthenol ointment is especially important in these cases. D-Panthenol ointment has proved its efficacy in dermatological and pediatric practice due to its significant clinical effectiveness and high safety both in the treatment and prevention of various pathological conditions of the skin, including diaper and atopic dermatitis in children.
Key words: skin, barrier-protective skin function, dermatoses, infants, D-Panthenol.
For citation: Tamrazova O.B., Kasyanova A.N., Zaplatnikov A.L. Features of infants’ skin care in dermatoses // RMJ. Medical Review. 2018. № 1(II). P. 80–84.
References
1. Захарова И. Н., Пшеничникова И. И., МачневаЕ.Б.Правильный уход за кожей новорожденных и детей раннего возраста: что нужно знать педиатру // Педиатрия. Приложение к журналу ConsiliumMedicum. 2016. № 1. С. 24‒30 [Zaharova I.N., Pshenichnikova I. I., MachnevaE.B.Pravil’nyj uhod za kozhej novorozhdennyh i detej rannego vozrasta: chto nuzhno znat’ pediatru // Pediatrija. Prilozhenie k zhurnalu ConsiliumMedicum. 2016. № 1. S. 24‒30 (in Russian)].
2. Leung A., Balaji S., KeswaniS.G. Biology and Function of Fetal and Pediatric Skin // FacialPlastSurgClinNorthAm. 2013. Vol. 21 (1). P. 1–6. doi: 10.1016/j.fsc.2012.10.001
3. Natsuga K. Epidermal Barriers // Cold Spring HarbPerspect Med. 2014. Vol. 4 (4). a018218. doi: 10.1101/cshperspect.a018218
4. Visscher M., Narendran V. The Ontogeny of Skin // Adv Wound Care (New Rochelle). 2014. Vol. 3 (4). P. 291‒303. doi: 10.1089/wound.2013.0467
5. Wang F., Zieman A., Coulombe P. S. Skin Keratins // Methods Enzymol. 2016. Vol. 568. P. 303–350. doi: 10.1016/bs.mie.2015.09.032
6. Loden M., Maibach H. I. Treatment of Dry Skin Syndrome. Springer-Verlag Berlin Heidelberg. 2012. 592 pp.
7. Chen Y. E., Tsao H. The skin microbiome: current perspectives and future challenges // J AmAcadDermatol. 2013. Vol. 69 (1). P. 143‒155. doi: 10.1016/j.jaad.2013.01.016
8. Agier J., Brzezinska-Blaszczyk E. Cathelicidinsand defensins regulatemast cell antimicrobial activity // PostepyHigMedDosw (Online). 2016. Vol. 70 (0). P. 618‒636.
9. Tran D., Tran P., Roberts K., et al. Microbicidal properties and cytocidal selectivity of rhesus macaque theta defensins // Antimicrob Agents Chemother. 2007. Vol. 52 (3). P. 944‒53. doi:10.1128/AAC.01090–07
10. Gallo R. L., Hooper L. V. Epithelial antimicrobial defence of the skin and intestine // NatRevImmunol. 2012. Vol. 12. P. 503e16. doi: 10.1038/nri3228
11. Zhang L., Guerrero-Juarez C.F., Hata T., et al. Dermal adipocytes protect against invasive Staphylococcus aureus skin infection // J InvestDermatol. 2015. Vol. 135. P. 90. doi: 10.1126/science.1260972
12. Pasparakis M., Haase I., Nestle F. O. Mechanisms regulating skin immunity and inflammation // NatRevImmunol. 2014. Vol. 14. P. 289e301.
13. Yamazaki Y., Nakamura Y., Núñez G. Role of the microbiota in skin immunity and atopic dermatitis // AllergolInt. 2017. Vol. 66 (4). P. 539‒544. doi: 10.1016/j.alit.2017.08.004.
14. Scharschmidt T. C., Fischbach M. A. What lives on our skin: ecology, genomics and therapeutic opportunities of the skin microbiome // Drug Discov Today Dis Mech. 2013. Vol.10. doi: 10.1016/j.ddmec.2012.12.003
15. Grice E. A., Kong H. H., Conlan S., et al. Topographical and temporal diversity of the human skin microbiome // Science. 2009. Vol. 324. P. 1190‒1192. doi: 10.1126/science.1171700
16. Pammi M., O’Brien J.L., Ajami N. J., et al. Development of the cutaneous microbiome in the preterm infant: A prospective longitudinal study // PLoS One. 2017. Vol. 12 (4). e0176669. doi: 10.1371/journal.pone.0176669
17. Grice E. A., Segre J. A. The skin microbiome // NatRevMicrobiol. 2011. Vol. 9. P. 244‒253. doi: 10.1038/nrmicro2537
18. Capone K. A., Dowd S. E., Stamatas G. N., Nikolovski J. Diversity of the human skin microbiome early in life // J InvestDermatol. 2011. Vol. 131 (10). P. 2026‒32. doi: 10.1038/jid.2011.168
19. Cogen A. L., Nizet V., Gallo R. L. Skin microbiota: a source of disease of defence // Br J Dermatol. 2008. Vol. 158 (3). P. 442–55. doi: 10.1111/j.1365‒2133.2008.08437.x.
20. Telofski L. S., Morello A. P., Mack Correa M. C., Stamatas G. N. The infant skin barrier: Can we preserve, protect, and enhance the barrier? // DermatolResPract. 2012. P. 198789. doi: 10.1155/2012/198789.
21. Visscher M. O., Adam R., Brink S., Odio M. Newborn infant skin: physiology, development, and care // ClinDermatol. 2015. Vol. 33. P. 271–280. doi: 10.1016/j.clindermatol.2014.12.003
22. Галлямова Ю. А. Пеленочный дерматит и травматизация кожи у детей // Лечащий врач. 2013. № 9. С. 56 [Galljamova Ju.A. Pelenochnyj dermatit i travmatizacija kozhi u detej // Lechashhij vrach. 2013. № 9. S. 56 (in Russian)].
23. Kutlubay Z., Tanakol A., Engyn B., et al. Newborn Skin: Common Skin Problems // Maedica (Buchar). 2017. Vol. 12 (1). P. 42–47.
24. Stamatas G. N., Nikolovski J., Mack M. C. Infant skin physiology and development during the first years of life: A review of recent findings based on in vivo studies // Int J CosmetSci. 2011. Vol. 33. P. 17‒24. doi: 10.1111/j.1468–2494.2010.00611.x.
25. Касихина Е. И. Пеленочный дерматит: факторы риска, особенности течения, лечения и профилактики // РМЖ. 2017. № 25 (5). С. 368‒372 [Kasihina E. I. Pelenochnyj dermatit: faktory riska, osobennosti techenija, lechenija i profilaktiki // RMZh. 2017. № 25 (5). S. 368‒372 (in Russian)].
26. Li C., Zhu Z., Dai Y. Diaper dermatitis: a survey of risk factors for children aged 1–24 months in china // J. Int. Med. Res. 2012. Vol. 40. P. 1752–1760. doi:10.1177/030006051204000514
27. Atherton D., Mills K. What can be done to keep babies’ skin healthy? // RCM Midwives. 2004. Vol. 7. P. 288–290.
28. Minami-Hori M., Honma M., Fujii M. Developmental alterations of physical properties and components of neonatal-infantile stratum corneum of upper thighs and diaper-covered buttocks during the 1st year of life // J DermatolSci. 2014. Vol. 73. P. 67‒73. doi: 10.1016/j.jdermsci.2013.08.015.
29. Blume-Peytavi U., Lavender T., Jenerowicz D., et al. Recommendations from a European Roundtable Meeting on Best Practice Healthy Infant Skin Care // PediatrDermatol. 2016. Vol. 33 (3). P. 311‒221. doi: 10.1111/pde.12819.
30. Shin H. T. Diaper dermatitis that does not quit // DermatolTher. 2005. Vol. 18. P. 124–135.
31. Jackson P. D. Diaper dermatitis. Protecting the bottom line // Adv Nurse Pract. 2010. Vol. 18. P. 38–41.
32. Visscher M., Odio M., Taylor T. Skin care in the NICU patient: effects of wipes versus cloth and water on stratum corneum integrity // Neonatology. 2009. Vol. 96. P. 226–234.
33. Danby S. G., Bedwell C., Cork M. Neonatal skin care and toxicology. In: Eichenfield L, Frieden IJ, eds. Neonatal and infant dermatology, 3rd ed. Philadelphia: Saunders/ Elsevier. 2013. P. 46–56.
34. Lavender T., Furber C., Campbell M. Effect on skin hydration of using baby wipes to clean the napkin area of newborn babies: assessor-blinded randomized controlled equivalence trial // BMC Pediatr. 2012. Vol. 12. P. 59. doi: 10.1186/1471‒2431‒12‒59
35. Ehretsmann C., Schaefer P., Adam R. Cutaneous tolerance of baby wipes by infants with atopic dermatitis, and comparison of the mildness of baby wipe and water in infant skin // J EurAcadDermatolVenereol. 2001. Vol. 15 (1). P. 16–21.
36. Chang M. W., Nakrani R. Six children with allergic contact dermatitis to methylisothiazolinone in wet wipes (baby wipes) // Pediatrics. 2014. Vol. 133. P. 434–438.
37. Федеральные клинические рекомендации по ведению больных атопическим дерматитом. Российское общество дерматовенерологов и косметологов. М. 2015 [Federal’nye klinicheskie rekomendacii po vedeniju bol’nyh atopicheskim dermatitom. Rossijskoe obshhestvo dermatovenerologov i kosmetologov. M. 2015 (in Russian)].
38. Garcia Bartels N., Scheufele R., Prosch F. Effect of standardized skin care regimens on neonatal skin barrier function in different body areas // PediatrDermatol. 2010. Vol. 27. P. 1–8.
39. Iarkowski L. E., Tierney N. K., Horowitz P. Tolerance of skin care regimen in healthy, full-term neonates // ClinCosmetInvestigDermatol. 2013. Vol. 6. P. 137–144. doi: 10.2147/CCID.S42559
40. Williams H. C., Chalmers J. R., Simpson E. L. Prevention of atopic dermatitis // F1000 MedRep. 2012. Vol. 4. P. 24. doi: 10.3410/M4–24
41. Denda M. Epidermal proliferative response induced by sodium dodecyl sulphate varies with environmental humidity // Br J Dermatol. 2001. Vol. 145. P. 252–257.
42. Foisy M., Boyle R. J., Chalmers J. R. et al. The prevention of eczema in infants and children: an overview of Cochrane and non-Cochrane reviews // Evid Based Child Health. 2011. Vol. 6. P. 1322–1339. doi: 10.1002/ebch.827
43. Simpson E. L., Berry T. M., Brown P. A., Hanifin J. M. A pilot study of emollient therapy for the primary prevention of atopic dermatitis // J Am Acad Dermatol. 2010. Vol. 63. P. 587–593. doi: 10.1016/j.jaad.2009.11.011.
44. Horimukai K., Morita K., Narita M. et al. Application of moisturizer to neonates prevents development of atopic dermatitis // J Allergy ClinImmunol. 2014. Vol. 134. P. 824–830. doi: 10.1016/j.jaci.2014.07.060.
45. Simpson E. L., Chalmers J. R., Hanifin J. M. et al. Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention // J Allergy ClinImmunol. 2014. Vol. 134. P. 818–823. doi: 10.1016/j.jaci.2014.08.005
46. Делягин В. М. Синдром сухой кожи // РМЖ. Педиатрия. 2012. № 16. С.827 [Deljagin V. M. Sindrom suhoj kozhi // RMZh. Pediatrija. 2012. № 16. S.827 (in Russian)].
47. Захарова И. Н., Мачнева Е. Б. Уход за кожей детей раннего возраста // Вопросы современной педиатрии. 2014. № 13 (2). С. 95–100 [Zaharova I.N., Machneva E. B. Uhod za kozhej detej rannego vozrasta // Voprosy sovremennoj pediatrii. 2014. № 13 (2). S. 95–100 (in Russian)].
48. Xhauflaire-Uhoda E., Macarenko E., Denooz R. et al. Skin protection creams in medical settings: successful or evil? // J Occup Med Toxicol. 2008. Vol. 3. P. 15.
49. Белоусов Н. А., Горелов А. В. Применение мази Д-Пантенол в лечении пеленочного дерматита у новорожденных детей // Вопр. совр. педиатр. 2002. № 1 (4). С. 96–98 [Belousov N.A., Gorelov A. V. Primeneniye mazi D-Pantenol v lechenii pelenochnogo dermatita u novorozhdennykh detey // Vopr. sovr. pediatr. 2002. № 1 (4). S. 96–98 (in Russian)].
50. Кешишян Е. С., Сахарова Е. С. Использование мази и крема Д-Пантенол для профилактики и лечения повреждений кожи у детей раннего возраста // Consilium Medicum. 2007. № 9 (1). С. 8–10 [Keshishyan Ye.S., Sakharova Ye.S. Ispol’zovaniye mazi i krema D-Pantenol dlya profilaktiki i lecheniya povrezhdeniy kozhi u detey rannego vozrasta // Consilium Medicum. 2007. № 9 (1). S. 8–10 (in Russian)].
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