Allergic rhinitis. Challenges of patients mangement
G.N. Nikiforova¹, T.G. Fedoskova², V.M. Svistushkin<sup>1

1</sup> Sechenov University, Moscow
² “National Research Center — Institute of Immunology” Federal Medical-Biological Agency of Russia, Moscow

The article describes the challenges of managing patients with allergic rhinitis. Allergic rhinitis (AR) is a disease that characterized by IgE-mediated inflammation of the nasal mucosa developing after contact with the allergen. The late diagnosis of AR is the most common problem among patients, which is due to a number of aspects — low appealability on the background of a mild illness, no recognition of allergic symptoms by primary care doctors, lack of possibility to conduct specific allergodiagnostics in most of polyclinics.
In addition, the article describes the main principles of AR therapy — the pathogenetic approach, complexity, step-by-step treatment and prevention of the disease. It is emphasized, that the role and place of different therapy methods should be determined by the efficacy of their use for the treatment of the symptoms and the disease as a whole, the risk of side effects and complications, and the cost of treatment. The article describes antihistamines, or H1-histamine blockers, as the preparations of the first choice in the therapy of AR. Thus, an ideal approach to the treatment of patients with AR should be individualized, with special attention given to identifying and excluding the AR triggers in all cases.

Key words: allergic rhinitis, histamine, H1-histamine blockers, anti-inflammatory effect, cetirizine, Cetrine.
For citation: Nikiforova G.N., Fedoskova T.G., Svistushkin V.M. Allergic rhinitis. Challenges of patients mangement // 
RMJ. 2018. № 8(I). P. 46–52.