Practical tips on counseling pregnant women with group B Streptococcus infection
DOI: 10.32364/2618-8430-2022-5-1-51-57
A.A. Pashchenko1, L.S. Dzhokhadze1, Yu.E. Dobrokhotova1, T.S. Kotomina2, A.N. Efremov2
1Pirogov Russian National Research Medical University, Moscow, Russian Federation
2Branch of the City Clinical Hospital No. 52, Moscow, Russian Federation
Interpretation of smears identified group B Streptococcus (S. agalactiae) in various titers in urogenital epithelium depending on gestation term and management of pregnant women requiring antibiotics are still disputable among inpatient and outpatient obstetricians and gynecologists. It was demonstrated that S. agalactiae persistence in pregnant women without timely antibacterial therapy during delivery to eliminate microbes is reliably associated with severe infectious complications in the early neonatal period (e.g., newborn meningitis or sepsis). This paper systematically reviews recent publications and analyzes current clinical guidelines of global professional medical associations on the colonization of the urogenital tract of pregnant women with group B Streptococcus. The authors provide recommendations on managing pregnant women with S. agalactiae infection depending on gestation terms and microbial count to improve the diagnosis and medical treatment algorithms. Principles of rational pharmacotherapy in these pregnant women (including those in the intranatal period) are addressed.
Keywords: group B streptococcus, S. agalactia, GBS colonization, systematic review, asymptomatic bacteriuria, rational pharmacotherapy, pregnant women.
For citation: Pashchenko A.A., Dzhokhadze L.S., Dobrokhotova Yu.E. et al. Practical tips on counseling pregnant women with group B Streptococcus infection. Russian Journal of Woman and Child Health. 2022;5(1):51–57 (in Russ.). DOI: 10.32364/2618-8430-2022-5-1-51-57.
About the authors:
Aleksandr A. Pashchenko — postgraduate student of the Department of Obstetrics and Gynecology of the Medical Faculty, Pirogov Russian National Research Medical University; 1, Ostrovityanov str., Moscow, 117437, Russian Federation; ORCID iD 0000-0003-0202-2740.
Lela S. Dhokhadze — C. Sc. (Med.), assistant of the Department of Obstetrics and Gynecology of the Medical Faculty, Pirogov Russian National Research Medical University; 1, Ostrovityanov str., Moscow, 117437, Russian Federation; ORCID iD 0000-0001-5389-7817.
Yuliya E. Dobrokhotova — Dr. Sc. (Med.), Professor, Head of the Department of Obstetrics and Gynecology of the Medical Faculty, Pirogov Russian National Research Medical University; 1, Ostrovityanov str., Moscow, 117437, Russian Federation; ORCID iD 0000-0002-7830-2290.
Tatyana S. Kotomina — C. Sc. (Med.), Head of the Maternity Department, Branch of the City Clinical Hospital No. 52; 11, Sosnovaya str., Moscow, 123182, Russian Federation; ORCID iD 0000-0002-5660-2380.
Aleksandr N. Efremov — obstetrician-gynecologist of the Postnatal Department, Branch of the City Clinical Hospital No. 52; 11, Sosnovaya str., Moscow, 123182, Russian Federation.
Contact information: Aleksandr A. Pashchenko, e-mail: al.pashenko2018@gmail.com.
Financial Disclosure: no authors have a financial or property interest in any material or method mentioned.
There is no conflict of interests.
Received 05.04.2021.
Revised 28.04.2021.
Accepted 25.05.2021.
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