Acute and recurrent cystitis. Difficult patient
DOI: 10.32364/2587-6821-2021-5-3-130-133
A.V. Tsareva
International Medical Center "Multi Clinic", Tomsk, Russian Federation
Urinary tract infections (UTIs) are among the most common infectious diseases that tend to recur and significantly worsen the life quality of patients with acute and recurrent cystitis. Modern clinical guidelines regulate the procedure for diagnosis and the main therapeutic algorithms in bacterial cystitis. Compliance with these guidelines allows doctors of different specialties to exclude neurological diseases manifested by urination disorders and prescribe adequate therapy. The article presents two clinical cases of patients treated with a dietary supplement containing a combination of Cran-Max Cranberry, D-mannose and vitamin D3. In a patient with viral cystitis associated with COVID-19, treatment with this dietary supplement allowed to stop dysuria and significantly improve the clinical condition. In another case, this dietary supplement proved to be a safe and effective method to solve the problem of recurrent infectious and inflammatory diseases of the urinary system.
Keywords: acute cystitis, recurrent cystitis, diagnosis of cystitis, dysuria, COVID-19-associated cystitis, antibiotic resistance.
For citation: Tsareva A.V. Acute and recurrent cystitis. Difficult patient. Russian Medical Inquiry. 2021;5(3):130–133. DOI: 10.32364/2587-6821-2021-5-3-130-133.
About the author:
Anna V. Tsareva — Cand. of Sci. (Med.), urologist, Head of the Urology Group, International Medical Center “Multi Clinic”; 9/1, Sibirskaya str., Tomsk, 634029, Russian Federation.
Contact information: Anna V. Tsareva, e-mail: docann81@mail.ru. Financial Disclosure: the author has no a financial or property interest in any material or method mentioned. There is no conflict of interests. Received 04.03.2021, revised 30.03.2021, accepted 22.04.2021.
2. Hooton T.M., Scholes D., Hughes J. et al. A prospective study of risk factors for symptomatic urinary tract infections in young women. N Engl J Med. 1996;335(7):468–474. DOI: 10.1056/NEJM199608153350703.
3. Лоран О.Б., Петров С.Б., Синякова Л.А., Перепанова Т.С. Эффективность применения фосфомицина трометамола (Монурала 3 г) в лечении больных хроническим рецидивирующим циститом. Эффективная фармакотерапия. Урология и нефрология. 2008;4:14–16. [Loran O.B., Petrov S.B., Sinyakova L.A., Perepanova T.S. The effectiveness of the use of fosfomycin trometamol (Monurala 3 g) in the treatment of patients with chronic recurrent cystitis. Effective pharmacotherapy. Urology and Nephrology. 2008;4:14–16 (in Russ.)].
4. Kunin C.M. Urinary tract infections: detection, prevention and management. 5th ed. Baltimore: Williams and Wilkins; 1997.
5. Foxman B. Recurring urinary tract infection: incidence and risk factors. Am J Public Health. 1990;80:331–333.
6. Hooton T.M., Stamm W.E. Diagnosis and treatment of uncomplicated urinary tract infection. Infect Dis Clin North Am. 1997;11(3):551–581.
7. Wagenlehner F., Wullt B., Ballarini S. et al. Social and economic burden of recurrent urinary tract infections and quality of life: a patient webbased study (GESPRIT) Expert Rev Pharmacoecon Outcomes Res. 2018;18(1):107–117. DOI: 10.1080/14737167.2017.1359543.
8. Matthews S.J., Lancaster J.W. Urinary tract infections in the elderly population. Am J Geriatr Pharmacother. 2011;9(5):286–309. DOI: 10.1016/j.amjopharm.2011.07.002.
9. Wagenlehner F.M.E., Hoyme U., Kaase M. et al. Uncomplicated urinary tract infections. Dtsch Arztebl Int. 2011;108(24):415–423. DOI: 10.3238/arztebl.2011.0415. 108: 415.
10. Alidjanov J.F., Abdufattaev U.A., Makhsudov S.A. et al. New self-reporting questionnaire to assess urinary tract infections and differential diagnosis: acute cystitis symptom score. Urol Int. 2014; 92 (2):230–236. DOI: 10.1159/000356177.
11. Chapple C.R. Is a voiding diary really necessary in 2014? Eur Urol. 2014;66(2):301–302. DOI: 10.1016/j.eururo.2014.05.001.
12. Foxman B. Urinary tract infection syndromes: occurrence, recurrence, bacteriology, risk factors, and disease burden. Infect Dis Clin North Am. 2014;28:1–13. DOI: 10.1016/j.idc.2013.09.003.
13. Kranz J., Schmidt S., Lebert C. et al. The 2017 update of the German clinical guideline on epidemiology, diagnostics, therapy, prevention, and management of uncomplicated urinary tract infections in adult patients: Part I. Urol Int. 2018;100(3):263–270. DOI: 10.1159/000486138.
14. Hooton T.M., Roberts P.L., Cox M.E., Stapleton A.E. Voided midstream urine culture and acute cystitis in premenopausal women. N Engl J Med. 2013;369(20):1883–1891. DOI: 10.1056/NEJMoa1302186.
15. Mumm J.-N., Andreas Osterman A., Ruzicka M. et al. Urinary frequency as a possibly overlooked symptom in COVID-19 patients: does SARS-CoV-2 cause viral cystitis? Eur Urol. 2020;78(4):624–628. DOI: 10.1016/j.eururo.2020.05.013.
16. Lamb L.E., Nivedita Dhar N., Timar R. et al. Chancellor COVID-19 inflammation results in urine cytokine elevation and causes COVID-19 associated cystitis (CAC). Med Hypotheses. 2020;145:110375. DOI: 10.1016/j.mehy.2020.110375.
17. Kranjčec B., Papeš D., Altarac S. D-mannose powder for prophylaxis of recurrent urinary tract infections in women: a randomized clinical trial. World J Urol. 2014;32(1):79–84. DOI: 10.1007/s00345-013-1091-6.
18. Meštrovi´c T., Matijaši´c M., Peri´c M. et al. The role of gut, vaginal, and urinary microbiome in urinary tract infections: from bench to bedside. Diagnostics (Basel). 2020;11(1):7. DOI: 10.3390/diagnostics11010007.
19. Tabasi M., Asadi Karam M.R., Habibi M. et al. Phenotypic assays to determine virulence factors of uropathogenic Escherichia coli (UPEC) isolates and their correlation with antibiotic resistance pattern. Osong Public Health Res Perspect. 2015;6(4):261–268. DOI: 10.1016/j.phrp.2015.08.002.
20. Bohbot J.-M. Results of a randomised, double-blind study on the prevention of recurrent cystitis with GynDelta®. The Gynaecologist’s and Obstetrician’s Journal. Special issue from the C.C.D. Laboratory. 2007.
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