Acute and recurrent cystitis. What do we know?

L.A. Khodyreva^1,2, A.V. Zaitsev¹, A.N. Bernikov¹, Yu.A. Kupriyanov^1,2, R.V. Stroganov³, O.A. Arefieva^2,3

¹A.I. Yevdokimov Moscow State University of Medicine and Dentistry, Moscow

²Research Institute for Healthcare and Medical Management of Moscow Healthcare Department, Moscow

³City Clinical Hospital named after S.I. Spasokukotsky, Moscow

The growing antibiotic resistance of urinary tract infection pathogens is an urgent problem worldwide. Rational use of antibacterial drugs and alternative non-antibacterial prevention of lower urinary tract infections are aimed at solving this problem. The article presents current data on the etiology, pathogenesis, diagnosis, treatment, and prevention of acute uncomplicated and recurrent lower urinary tract infection. The article also shows the results of clinical studies on the use of proanthocyanidins, D-mannose and vitamin D₃ in the complex treatment and prevention of acute infectious and inflammatory process in the urinary bladder. According to the scientific literature, the mechanism of action of alternative drugs and their efficacy in reducing the frequency of relapses is demonstrated.

Keywords: urinary tract infection, urinary bladder, recurrent infection, postcoital prevention, proanthocyanidins, D-mannose, vitamin D₃.

For citation: Khodyreva L.A., Zaitsev A.V., Bernikov A.N. et al. Acute and recurrent cystitis. What do we know? RMJ. 2020;11:69–74.