Сlinical guidelines update on the treatment of patients with osteoarthritis in 2019

L.I. Alekseeva

V.A. Nasonova Research Institute of Rheumatology, Moscow

Osteoarthritis (OA) is a chronic progressive disease, which requires a comprehensive approach to its treatment, depending on the disease severity. An in-depth study of disease pathogenetic pathways has led to the awareness that OA includes several disease subtypes. The OA changing perception sets new goals for its treatment, namely, guidelines creation for a particular OA phenotype. At the latest ESCEO congress in 2019, held in Paris, data on updating the previous guidelines based on the GRADE evidence system and new systematic reviews, and meta-analyses were presented. Treatment of patients with OA should be carried out using non-pharmacological and pharmacological methods combination. The updated algorithm for treating patients with OA based on evidence-based medicine principles offers a comprehensive approach to OA treatment. Adding that by using the GRADE evidence system it justifies the need for basic therapy with symptomatic slow-acting drugs (SYSADOA) at the first treatment stage, with the stepwise prescription of drugs. It will certainly be useful for practicing physicians.

Keywords: osteoarthritis, clinical guidelines, treatment, NSAIDs, glucosamine sulfate, Sustaguard Artro, chondroitin sulfate, Chondroguard.
For citation: Alekseeva L.I. Сlinical guidelines update on the treatment of patients with osteoarthritis in 2019. RMJ. 2019;4:2–6.