Acute tonsillopharyngitis: possibilities of combined treatment
DOI: 10.32364/2587-6821-2024-8-8-6
O.V. Filippova
I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation
Acute sore throat is a prevalent concern among patients visiting medical specialists and pharmacies alike. The primary etiology is commonly a combination of acute tonsillitis, characterized by inflammation of the palatine tonsils, and acute pharyngitis, involving inflammation of the posterior and lateral pharyngeal walls. Typically, systemic antibiotic therapy is not necessary for managing these cases. The predominant treatment approach involves the prescription of topical antiseptics delivered through lozenges and sprays. Each formulation, along with its active constituents, has specific attributes that must be considered during treatment tactics.
Topical antiseptic therapy offers several benefits, including direct efficacy at the site of inflammation, minimal systemic absorption, and a low potential for developing microbial resistance. A rational therapeutic strategy involves using a combination of ambazone lozenges, which exert a bacteriostatic effect against various pathogenic microorganisms responsible for acute tonsillopharyngitis, and benzydamine spray, which provides a complementary topical anti-inflammatory action to enhance ambazone's antimicrobial properties. This combination effectively targets multiple aspects of the pathological process, offering a well-rounded therapeutic advantage. The article supports the strategic implementation of this combination therapy.
Keywords: sore throat, pharyngitis, tonsillopharyngitis, ambazone, benzydamine, topical therapy.
For citation: Filippova O.V. Acute tonsillopharyngitis: possibilities of combined treatment. Russian Medical Inquiry. 2024;8(8):477–483 (in Russ.). DOI: 10.32364/2587-6821-2024-8-8-6.
About the author:
Olga V. Filippova — Dr. Sci. (Med.), Professor of the Department of Industrial Pharmacy, I.M. Sechenov First Moscow State Medical University (Sechenov University): 8, build. 2, Trubetskaya str., Moscow, 119991, Russian Federation; ORCID iD 0000-0001-9470-6335.
Contact information: Olga V. Filippova, e-mail: filippova_o_v_3@staff.sechenov.ru.
Financial Disclosure: the author has no a financial or property interest in any material or method mentioned.
There is no conflict of interest.
Received 15.07.2024.
Revised 07.08.2024.
Accepted 30.08.2024.
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